FSHβ Antibody (F2): sc-66127

FSHβ Antibody (F2) is a mouse monoclonal IgG antibody that detects FSHβ of human origin by western blotting (WB). Anti-FSHβ antibody (F2) is available in non-conjugated form. Follicle-stimulating hormone (FSH), also known as follitropin, is a crucial glycoprotein hormone that plays a significant role in reproductive processes. FSH is composed of two subunits: a common alpha subunit and a unique beta subunit, with the latter being essential for hormone specificity and biological activity. FSHβ subunit is vital for hormone interaction with follicle-stimulating hormone receptor (FSHR), predominantly found in Sertoli cells in the testes and granulosa cells in the ovaries. This interaction is critical for regulating gametogenesis and maintaining reproductive health. The precise structure of FSHβ, including glycosylation patterns, influences stability and activity, making FSHβ an important target for research in fertility and hormonal regulation. FSHβ (F2) antibody is an invaluable tool for studying FSH signaling dynamics and implications in various reproductive disorders.

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FSHβ Antibody (F2) References:

1. Mutations of follicle stimulating hormone-beta and its receptor in human and mouse: genotype/phenotype.  |  Layman, LC. and McDonough, PG. 2000. Mol Cell Endocrinol. 161: 9-17. PMID: 10773385
2. Mutations in the follicle-stimulating hormone-beta (FSH beta) and FSH receptor genes in mice and humans.  |  Layman, LC. 2000. Semin Reprod Med. 18: 5-10. PMID: 11299519
3. All-or-none N-glycosylation in primate follicle-stimulating hormone beta-subunits.  |  Bousfield, GR., et al. 2007. Mol Cell Endocrinol. 260-262: 40-8. PMID: 17079072
4. Hormonal signaling to follicle stimulating hormone beta-subunit gene expression.  |  Melamed, P. 2010. Mol Cell Endocrinol. 314: 204-12. PMID: 19481581
5. Targeted paclitaxel nanoparticles modified with follicle-stimulating hormone β 81-95 peptide show effective antitumor activity against ovarian carcinoma.  |  Zhang, X., et al. 2013. Int J Pharm. 453: 498-505. PMID: 23811008
6. Pituitary gonadotrophic hormone synthesis, secretion, subunit gene expression and cell structure in normal and follicle-stimulating hormone β knockout, follicle-stimulating hormone receptor knockout, luteinising hormone receptor knockout, hypogonadal and ovariectomised female mice.  |  Abel, MH., et al. 2014. J Neuroendocrinol. 26: 785-95. PMID: 25039914
7. Molecular analysis of the koala reproductive hormones and their receptors: gonadotrophin-releasing hormone (GnRH), follicle-stimulating hormone β and luteinising hormone β with localisation of GnRH.  |  Busby, ER., et al. 2014. J Neuroendocrinol. 26: 870-87. PMID: 25200132
8. Molecular characterization of the Chinese alligator follicle-stimulating hormone β subunit (FSHβ) and its expression during the female reproductive cycle.  |  Zhang, R., et al. 2015. Comp Biochem Physiol B Biochem Mol Biol. 183: 49-57. PMID: 25626184
9. Transcriptional regulation of follicle-stimulating hormone β-subunit in marmoset by an alternate distal promoter.  |  Kutteyil, SS., et al. 2017. Gen Comp Endocrinol. 246: 331-336. PMID: 28062307
10. Decay of follicle-stimulating hormone-beta messenger RNA in the presence of transcriptional inhibitors and/or inhibin, activin, or follistatin.  |  Attardi, B. and Winters, SJ. 1993. Mol Endocrinol. 7: 668-80. PMID: 7686252

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FSHβ Antibody (F2) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-FSHβ Antibody (F2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FSHβ Antibody (F2) Specifications

Alternate Product Name: FSHβ

Product Clone Name: F2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG

Amino Acids:

Epitope Target: FSHβ

Epitope Species: human

Product Reactivity/Detection: FSHβ

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB

Vialing Information: Each vial contains 100 µg IgG in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for FSHβ Antibody (F2): N/A

The preferred FSHβ antibody is FSHβ Antibody (C-12): sc-374452.