FSHα Antibody (BGN/F62/01): sc-80795

FSHα Antibody (BGN/F62/01) is a mouse monoclonal IgG1 antibody that detects the FSH alpha protein of human origin by enzyme-linked immunosorbent assay (ELISA). Anti-FSHα antibody (BGN/F62/01) is available as a non-conjugated format. Follicle-stimulating hormone (FSH), also known as follitropin, is a crucial glycoprotein hormone that plays a significant role in reproductive processes. FSH is part of a family of hormones that includes luteinizing hormone and thyroid-stimulating hormone, all secreted by the pituitary gland. FSH exists as a heterodimer, composed of a common α subunit and a unique β subunit, which together facilitate FSH binding to follicle-stimulating hormone receptor (FSHR). FSHα is essential for receptor binding, while FSHβ enhances the stability of this interaction, thereby regulating various physiological processes such as gametogenesis and hormone secretion. FSH and FSHR are primarily localized to Sertoli cells in the testes, where FSH is vital for spermatogenesis and overall male fertility. FSH′s ability to modulate these processes underscores FSH′s importance in reproductive health, making FSHα (BGN/F62/01) antibody an invaluable tool for researchers studying fertility and hormonal regulation.

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FSHα Antibody (BGN/F62/01) References:

1. Human follitropin heterodimerization and receptor binding structural motifs: identification and analysis by a combination of synthetic peptide and mutagenesis approaches.  |  Dias, JA. 1996. Mol Cell Endocrinol. 125: 45-54. PMID: 9027342
2. Expression of biologically active fusion genes encoding the common alpha subunit and either the CG beta or FSH beta subunits: role of a linker sequence.  |  Sugahara, T., et al. 1996. Mol Cell Endocrinol. 125: 71-7. PMID: 9027345
3. Structural and functional characterisation of hFSH and hLH isoforms.  |  Stanton, PG., et al. 1996. Mol Cell Endocrinol. 125: 133-41. PMID: 9027351
4. The human follitropin alpha-subunit C terminus collaborates with a beta-subunit cystine noose and an alpha-subunit loop to assemble a receptor-binding domain competent for signal transduction.  |  Arnold, CJ., et al. 1998. Biochemistry. 37: 1762-8. PMID: 9485301
5. The basolateral localization signal of the follicle-stimulating hormone receptor.  |  Beau, I., et al. 1998. J Biol Chem. 273: 18610-6. PMID: 9660834
6. Localization of human follicle-stimulating hormone in the testis.  |  Baccetti, B., et al. 1998. FASEB J. 12: 1045-54. PMID: 9707177

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FSHα Antibody (BGN/F62/01) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-FSHα Antibody (BGN/F62/01) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FSHα Antibody (BGN/F62/01) Specifications

Alternate Product Name: FSHα

Product Clone Name: BGN/F62/01

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: FSHα

Epitope Species: human

Product Reactivity/Detection: FSHα

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: ELISA

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for FSHα Antibody (BGN/F62/01): N/A