FGF-20 Antibody (F-1): sc-398722

FGF-20 Antibody (F-1) is a mouse monoclonal IgG2b antibody that detects fibroblast growth factor 20 (FGF-20) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FGF-20 is a member of the fibroblast growth factor (FGF) family, which plays a crucial role in various biological processes, including cell proliferation, differentiation, and survival. Anti-FGF-20 antibody (F-1) is particularly useful for studying FGF-20′s involvement in the development of the central nervous system and potential role in neurogenesis and neuronal survival. FGF-20 is known to interact with specific receptors, such as FGFR-1 and FGFR-2, which are essential for mediating signaling pathways. These interactions are vital for proper cellular communication and can influence various physiological processes, including tissue repair and regeneration. FGF-20′s ability to promote cell survival and growth makes FGF-20 a significant factor in both developmental biology and potential therapeutic applications, particularly in neurodegenerative diseases. FGF-20 monoclonal antibody (F-1) is an invaluable tool for researchers studying the intricate roles of FGFs in health and disease.

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FGF-20 Antibody (F-1) References:

1. FGF-20, a novel neurotrophic factor, preferentially expressed in the substantia nigra pars compacta of rat brain.  |  Ohmachi, S., et al. 2000. Biochem Biophys Res Commun. 277: 355-60. PMID: 11032730
2. Gene-gene interaction between FGF20 and MAOB in Parkinson disease.  |  Gao, X., et al. 2008. Ann Hum Genet. 72: 157-62. PMID: 18205889
3. FGF20 and Parkinson's disease: no evidence of association or pathogenicity via alpha-synuclein expression.  |  Wider, C., et al. 2009. Mov Disord. 24: 455-9. PMID: 19133659
4. Fibroblast growth factor 20 (FGF20) gene polymorphism and risk of Parkinson's disease: a meta-analysis.  |  Zhu, R., et al. 2014. Neurol Sci. 35: 1889-94. PMID: 24942208
5. FGF20-Expressing, Wnt-Responsive Olfactory Epithelial Progenitors Regulate Underlying Turbinate Growth to Optimize Surface Area.  |  Yang, LM., et al. 2018. Dev Cell. 46: 564-580.e5. PMID: 30100263
6. Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner.  |  Yang, LM., et al. 2019. PLoS Genet. 15: e1008254. PMID: 31276493
7. Analysis of FGF20-regulated genes in organ of Corti progenitors by translating ribosome affinity purification.  |  Yang, LM., et al. 2020. Dev Dyn. 249: 1217-1242. PMID: 32492250
8. FGF20 Protected Against BBB Disruption After Traumatic Brain Injury by Upregulating Junction Protein Expression and Inhibiting the Inflammatory Response.  |  Chen, J., et al. 2020. Front Pharmacol. 11: 590669. PMID: 33568994
9. Quantitative assessment of the effect of FGF20 rs1721100 and rs12720208 variant on the risk of sporadic Parkinson's disease: a meta-analysis.  |  Quan, W., et al. 2022. Neurol Sci. 43: 3145-3152. PMID: 34845561
10. Skeletal dysmorphology and mineralization defects in Fgf20 KO mice.  |  Dlugosova, S., et al. 2024. Front Endocrinol (Lausanne). 15: 1286365. PMID: 39129916

The preferred FGF-9 antibody is FGF-9 Antibody (D-8): sc-8413.