FGF-9 Antibody (D-8): sc-8413

FGF-9 Antibody (D-8) is a mouse monoclonal IgG3 antibody that detects fibroblast growth factor 9 (FGF-9) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). FGF-9 Antibody (D-8) is available in a non-conjugated form, allowing for versatile use in various experimental setups. FGF-9 plays a crucial role in embryonic development and tissue repair by promoting cell proliferation and differentiation, particularly in mesenchymal and epithelial tissues. FGF-9 is primarily located in the extracellular space, where FGF-9 binds to specific fibroblast growth factor receptors (FGFRs) on the cell surface, initiating signaling pathways that regulate cellular processes such as migration, survival, and angiogenesis. FGF-9 interaction with receptors is vital for normal physiological functions and has implications in various pathological conditions, including cancer and tissue fibrosis. Additionally, FGF-9 is known to interact with other members of the fibroblast growth factor family, such as FGF-1 and FGF-2, which can further modulate activity and influence cellular responses. FGF-9 ability to form complexes with these proteins underscores importance in the intricate network of growth factor signaling, making FGF-9 (D-8) monoclonal antibody an essential tool for researchers studying developmental biology and disease mechanisms.

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FGF-9 Antibody (D-8) References:

1. Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells.  |  Tanaka, A., et al. 1992. Proc Natl Acad Sci U S A. 89: 8928-32. PMID: 1409588
2. Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors.  |  Dionne, CA., et al. 1990. EMBO J. 9: 2685-92. PMID: 1697263
3. Recent developments in the cell biology of basic fibroblast growth factor.  |  Rifkin, DB. and Moscatelli, D. 1989. J Cell Biol. 109: 1-6. PMID: 2545723
4. Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family.  |  Marics, I., et al. 1989. Oncogene. 4: 335-40. PMID: 2649847
5. An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family.  |  Delli Bovi, P., et al. 1987. Cell. 50: 729-37. PMID: 2957062
6. Sequence, topography and protein coding potential of mouse int-2: a putative oncogene activated by mouse mammary tumour virus.  |  Moore, R., et al. 1986. EMBO J. 5: 919-24. PMID: 3013624
7. The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors.  |  Zhan, X., et al. 1988. Mol Cell Biol. 8: 3487-95. PMID: 3211147
8. FGF9 Recruits β-Catenin to Increase Hepatic ECM Synthesis and Promote NASH-Driven HCC.  |  Zhang, L., et al. 2023. Adv Sci (Weinh). 10: e2301166. PMID: 37566761
9. FGF9 is required for Purkinje cell development and function in the cerebellum.  |  He, P., et al. 2024. iScience. 27: 109039. PMID: 38352230
10. Fgf9 regulates bone marrow mesenchymal stem cell fate and bone-fat balance in osteoporosis by PI3K/AKT/Hippo and MEK/ERK signaling.  |  Chen, M., et al. 2024. Int J Biol Sci. 20: 3461-3479. PMID: 38993574
11. Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property.  |  Miyamoto, M., et al. 1993. Mol Cell Biol. 13: 4251-9. PMID: 8321227
12. Mouse fibroblast growth factor 10: cDNA cloning, protein characterization, and regulation of mRNA expression.  |  Beer, HD., et al. 1997. Oncogene. 15: 2211-8. PMID: 9393979

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FGF-9 Antibody (D-8) has 13 citations in a variety of scientific publications.

Primary antibodies like Anti-FGF-9 Antibody (D-8) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FGF-9 Antibody (D-8) Specifications

Alternate Product Name: FGF-9

Product Clone Name: D-8

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃

Amino Acids: 1-208

Epitope Target: FGF-9

Epitope Species: human

Product Reactivity/Detection: precursor and mature FGF-9

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₃ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 13 citations in various scientific publications

Available Conjugates/Forms for FGF-9 Antibody (D-8): N/A