FBL4 Antibody (D-9): sc-393772
- FBL4 Antibody (D-9) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 31-330 mapping near the N-terminus of FBL4 of human origin
- recommended for detection of FBL4 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for FBL4 Antibody (D-9) for WB applications. These reagents are now offered in bundles with FBL4 Antibody (D-9) (see ordering information below).
FBL4 Antibody (D-9) is a mouse monoclonal IgG1 antibody that detects FBL4 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FBL4 is a 621 amino acid protein encoded by the human gene FBXL4 and is characterized by its unique structure, which includes a 40 amino acid F-box region and eight leucine-rich repeats (LRRs). The presence of the F-box domain is crucial as FBL4 functions as a key component of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex, facilitating the recognition and recruitment of substrate proteins for ubiquitination. This process is vital for regulating various cellular functions, including the cell cycle, immune responses, and signaling pathways, by targeting specific proteins such as cyclins and β-catenin for proteasomal degradation. FBL4 is predominantly localized in the cytoplasm near the nucleus and is expressed in several human tissues, including the heart, kidney, liver, lung, pancreas, and placenta, although notably absent in skeletal muscle. FBL4 (D-9) antibody provides a reliable tool for researchers investigating the role of FBL4 in cellular processes and biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FBL4 Antibody (D-9) | sc-393772 | 200 µg/ml | $316.00 | |||
FBL4 Antibody (D-9): m-IgG Fc BP-HRP Bundle | sc-538306 | 200 µg Ab; 10 µg BP | $354.00 | |||
FBL4 Antibody (D-9): m-IgGκ BP-HRP Bundle | sc-535888 | 200 µg Ab; 40 µg BP | $354.00 | |||
FBL4 Antibody (D-9): m-IgG1 BP-HRP Bundle | sc-545630 | 200 µg Ab; 20 µg BP | $354.00 |