Ezrin Antibody (C-4): sc-271541
- Ezrin Antibody (C-4) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 1-300 mapping at the N-terminus of Ezrin of human origin
- recommended for detection of Ezrin, Radixin and Moesin of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See Ezrin (H-4): sc-398542 for Ezrin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Ezrin Antibody (C-4) for WB and IHC(P) applications. These reagents are now offered in bundles with Ezrin Antibody (C-4) (see ordering information below).
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SEE ALSO...
Ezrin Antibody (C-4) is a mouse monoclonal IgG1 antibody that detects Ezrin in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Ezrin is a crucial member of the ERM (ezrin, radixin, moesin) protein family, which plays a vital role in linking the cytoskeleton to the plasma membrane, thereby facilitating cellular processes such as cell shape maintenance, motility, and signaling. Ezrin is predominantly localized beneath the plasma membrane, where anti-Ezrin antibody (C-4) can detect scaffold assemblies for signaling complexes, particularly in response to growth factor stimulation. Ezrin serves as a significant substrate for various protein-tyrosine kinases, including the epidermal growth factor receptor, which underscores Ezrin′s importance in signal transduction pathways that regulate cell proliferation and differentiation. Additionally, Ezrin functions as an anchoring protein for cAMP-dependent protein kinase, known as AKAP78, which is essential for the spatial organization of signaling molecules within the cell. The distinct phosphorylation patterns exhibited by Ezrin, Moesin, and Radixin, despite their high homology, suggest specialized roles in different cellular contexts, making Ezrin (C-4) antibody an invaluable tool for studying these dynamic processes in various biological systems.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ezrin Antibody (C-4) | sc-271541 | 200 µg/ml | $322.00 | |||
Ezrin Antibody (C-4): m-IgG Fc BP-HRP Bundle | sc-537659 | 200 µg Ab; 10 µg BP | $361.00 | |||
Ezrin Antibody (C-4): m-IgGκ BP-HRP Bundle | sc-534993 | 200 µg Ab; 40 µg BP | $361.00 | |||
Ezrin Antibody (C-4): m-IgG1 BP-HRP Bundle | sc-545288 | 200 µg Ab; 20 µg BP | $361.00 |