EVC Antibody (C-6): sc-377157
- EVC Antibody (C-6) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 181-441 mapping within an internal region of EVC of mouse origin
- recommended for detection of EVC of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for EVC Antibody (C-6) for WB and IHC(P) applications. These reagents are now offered in bundles with EVC Antibody (C-6) (see ordering information below).
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EVC Antibody (C-6) is a mouse monoclonal IgG1 antibody that detects EVC in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). EVC, or Ellis-van Creveld syndrome protein, plays a crucial role in the hedgehog signaling pathway, which is essential for proper embryonic development and tissue patterning. EVC protein′s structure includes a leucine zipper and a transmembrane domain, which are vital for mediating cellular signaling processes. Disruptions in the EVC gene can lead to significant developmental disorders, including short-limb dwarfism and ectodermal dysplasia, highlighting EVC′s importance in normal skeletal and organ development. Furthermore, the EVC gene has been associated with Weyers acrodental dysostosis, a condition characterized by distinct facial and limb abnormalities, underscoring EVC′s critical role in maintaining developmental integrity. Anti-EVC antibody (C-6) is an invaluable tool for researchers studying these conditions and the underlying mechanisms of the hedgehog signaling pathway.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EVC Antibody (C-6) | sc-377157 | 200 µg/ml | $322.00 | |||
EVC Antibody (C-6): m-IgG Fc BP-HRP Bundle | sc-538022 | 200 µg Ab; 10 µg BP | $361.00 | |||
EVC Antibody (C-6): m-IgGκ BP-HRP Bundle | sc-535543 | 200 µg Ab; 40 µg BP | $361.00 |