EMAP II Antibody (A-10): sc-393672
- EMAP II Antibody (A-10) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 231-262 within an internal region of EMAP II of mouse origin
- recommended for detection of precursor and mature EMAP II of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including bovine
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for EMAP II Antibody (A-10) for WB applications. These reagents are now offered in bundles with EMAP II Antibody (A-10) (see ordering information below).
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SEE ALSO...
EMAP II Antibody (A-10) is a mouse monoclonal IgG2a antibody that detects endothelial monocyte-activating polypeptide (EMAP II) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). EMAP II plays a crucial role as a chemoattractant cytokine for monocytes and granulocytes, particularly in apoptosis-induced inflammation. EMAP II is primarily located in the extracellular space, where various cell types, including tumor cells, secrete this protein to modulate immune responses and promote angiogenesis in the tumor microenvironment. EMAP II release from tumor-associated vasculature enhances sensitivity to tumor necrosis factor, influencing the overall inflammatory response. EMAP II is synthesized as a precursor protein, proEMAP II, which undergoes proteolytic cleavage to yield the mature, biologically active form of the cytokine. This post-translational modification activates the cytokine and enables interaction with specific proteins involved in inflammatory signaling pathways, amplifying the immune response in pathological conditions. Anti-EMAP II antibody (A-10) serves as an essential tool for researchers studying this cytokine′s intricate roles in cancer biology and immune regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EMAP II Antibody (A-10) | sc-393672 | 200 µg/ml | $322.00 | |||
EMAP II Antibody (A-10): m-IgG Fc BP-HRP Bundle | sc-538280 | 200 µg Ab; 10 µg BP | $361.00 | |||
EMAP II Antibody (A-10): m-IgGκ BP-HRP Bundle | sc-535858 | 200 µg Ab; 40 µg BP | $361.00 | |||
EMAP II Antibody (A-10): m-IgG2a BP-HRP Bundle | sc-548255 | 200 µg Ab; 10 µg BP | $361.00 | |||
EMAP II (A-10) Neutralizing Peptide | sc-393672 P | 100 µg/0.5 ml | $69.00 |