EGFR Antibody (3i4): sc-71032
- EGFR Antibody (3i4) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 985-996 of EGFR of human origin
- recommended for detection of EGFR of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See EGFR (A-10): sc-373746 for EGFR antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for EGFR Antibody (3i4) for WB and IHC(P) applications. This reagent is now offered in a bundle with EGFR Antibody (3i4) (see ordering information below).
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EGFR Antibody (3i4) is a mouse monoclonal IgG1 antibody that detects amino acids 985-996 of EGFR of human origin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. EGFR, or epidermal growth factor receptor, plays a crucial role in cell signaling pathways that regulate cell proliferation, survival, and differentiation. EGFR is primarily located on the cell membrane, where EGFR interacts with various ligands, including epidermal growth factor and transforming growth factor alpha, leading to receptor dimerization and activation of its intrinsic tyrosine kinase activity. EGFR′s location is crucial for initiating signaling cascades that influence critical cellular processes, such as organ development and tissue repair, by regulating epithelial cell proliferation during embryogenesis and promoting cellular migration and proliferation at wound sites. However, aberrant activation of EGFR is frequently associated with the progression of various cancers, making EGFR a significant target for therapeutic intervention. Anti-EGFR antibody (3i4) is particularly valuable for researchers studying the mechanisms of cancer biology and the potential for targeted therapies, as anti-EGFR antibody (3i4) can identify and quantify EGFR expression levels in different experimental contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EGFR Antibody (3i4) | sc-71032 | 200 µg/ml | $322.00 | |||
EGFR Antibody (3i4): m-IgG Fc BP-HRP Bundle | sc-539331 | 200 µg Ab; 10 µg BP | $361.00 |