EDG-1/S1P1/S1PR1 Antibody (F-6): sc-271423
- EDG-1/S1P1/S1PR1 Antibody (F-6) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 302-351 near the C-terminus of EDG-1 of human origin
- recommended for detection of EDG-1 of human origin by WB, IP, IF and ELISA
- See EDG-1/S1P1/S1PR1 (A-6): sc-48356 for EDG-1/S1P1/S1PR1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for EDG-1/S1P1/S1PR1 Antibody (F-6) for WB applications. These reagents are now offered in bundles with EDG-1/S1P1/S1PR1 Antibody (F-6) (see ordering information below).
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SEE ALSO...
EDG-1 Antibody (F-6) is a mouse monoclonal IgG1 antibody that detects EDG-1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). EDG-1, a member of the endothelial differentiation gene family of G protein-coupled receptors, plays a crucial role in mediating cellular responses to lysophospholipid signaling, particularly through its high-affinity binding to sphingosine-1-phosphate. This receptor is predominantly expressed in glioma cells and couples with Gi proteins, which activate the Akt signaling pathway, promoting cell survival and growth. EDG-1′s location in glioma cells significantly impacts tumor progression and modulation of the tumor microenvironment. Understanding EDG-1′s function and signaling mechanisms is vital for developing targeted therapies in cancer treatment, particularly in gliomas where aberrant signaling pathways contribute to malignancy. EDG-1 (F-6) antibody serves as an essential tool for scientists investigating lysophospholipid receptors in various biological processes and disease states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EDG-1/S1P1/S1PR1 Antibody (F-6) | sc-271423 | 200 µg/ml | $322.00 | |||
EDG-1/S1P1/S1PR1 Antibody (F-6): m-IgG Fc BP-HRP Bundle | sc-537630 | 200 µg Ab; 10 µg BP | $361.00 | |||
EDG-1/S1P1/S1PR1 Antibody (F-6): m-IgGκ BP-HRP Bundle | sc-534955 | 200 µg Ab; 40 µg BP | $361.00 | |||
EDG-1/S1P1/S1PR1 Antibody (F-6): m-IgG1 BP-HRP Bundle | sc-545270 | 200 µg Ab; 20 µg BP | $361.00 | |||
EDG-1/S1P1/S1PR1 (F-6) Neutralizing Peptide | sc-271423 P | 100 µg/0.5 ml | $69.00 |