Date published: 2025-12-8

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EDG-1 Activators

EDG-1 Activators form a distinctive category of chemical compounds known for their capability to modulate the activity of endothelial differentiation gene-1 (EDG-1) receptors. This chemical class functions by interacting with and enhancing the signaling pathways associated with EDG-1, which belongs to the lysophospholipid receptor family and plays a pivotal role in mediating cellular responses to lysophospholipids. EDG-1 is recognized for its involvement in various biological processes, including cell migration, proliferation, and vascular development. EDG-1 Activators exert their influence through specific molecular interactions that may amplify the downstream effects of EDG-1-mediated signaling, contributing to the fine-tuning of cellular behaviors, vascular integrity, and tissue homeostasis. The intricate mechanisms through which EDG-1 Activators impact EDG-1-related pathways are subjects of ongoing scientific exploration, providing insights into the intricate interplay between cell signaling and cellular responses to extracellular cues. The specific ways in which this chemical class engages with EDG-1 highlight its significance in unraveling the complexities of cellular communication and enhancing our understanding across various scientific domains.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

D-erythro-Sphingosine-1-phosphate

26993-30-6sc-201383
sc-201383D
sc-201383A
sc-201383B
sc-201383C
1 mg
2 mg
5 mg
10 mg
25 mg
$162.00
$316.00
$559.00
$889.00
$1693.00
7
(1)

S1P itself can induce S1PR1 expression. S1P is the natural ligand for S1PR1, and its binding activates signaling pathways involved in cell migration and angiogenesis.

FTY720 Phosphate

402615-91-2sc-205332
sc-205332A
1 mg
5 mg
$177.00
$809.00
6
(1)

FTY720 (Fingolimod) is known to induce the expression of the edg-1 gene. The edg-1 gene encodes the sphingosine 1-phosphate receptor 1 (S1P1), and FTY720 is a sphingosine analog that acts as a modulator of S1P1 signaling.

FTY720 (S)-Phosphate

402616-26-6sc-205331
sc-205331A
500 µg
1 mg
$113.00
$218.00
3
(1)

FTY720 (Fingolimod) is known to induce the expression of the edg-1 gene. The edg-1 gene encodes the sphingosine 1-phosphate receptor 1 (S1P1), and FTY720 is a sphingosine analog that acts as a modulator of S1P1 signaling.

SEW2871

256414-75-2sc-203251
sc-203251A
5 mg
10 mg
$37.00
$52.00
1
(0)

SEW2871 is a synthetic compound that acts as a selective agonist for the sphingosine 1-phosphate receptor 1 (S1P1), which is encoded by the edg-1 gene. When SEW2871 binds to the S1P1 receptor, it triggers a series of intracellular signaling events that are characteristic of S1P1 activation. These signaling pathways are involved in various cellular processes, including immune cell migration, vascular integrity, and other functions related to the immune and cardiovascular systems.

RP 001 hydrochloride

1306761-53-4sc-362791
sc-362791A
10 mg
50 mg
$215.00
$906.00
(0)

RP 001 hydrochloride is an acid halide distinguished by its potent electrophilic nature, which facilitates swift acylation with nucleophiles. Its unique electronic configuration allows for enhanced reactivity, promoting specific molecular interactions that drive selective transformations. The compound exhibits notable stability in transient intermediates, optimizing reaction kinetics. Furthermore, its solubility characteristics enable diverse solvent interactions, significantly impacting reaction mechanisms and product yields.

CYM 5442 hydrochloride

1094042-01-9sc-311309
sc-311309A
10 mg
50 mg
$214.00
$887.00
(1)

CYM 5442 hydrochloride is a selective agonist of the sphingosine 1-phosphate receptor 1 (S1P1), which is encoded by the edg-1 gene. CYM 5442 hydrochloride is used to activate S1P1 signaling and modulate various cellular processes associated with immune regulation, inflammation, and vascular integrity.

TC-SP 14

1257093-40-5sc-391020
10 mg
$195.00
(0)

TC-SP 14 is an acid halide characterized by its exceptional reactivity due to a highly polarized carbonyl group, which enhances its electrophilic properties. This compound engages in rapid acylation reactions, demonstrating a preference for specific nucleophiles. Its unique steric and electronic features facilitate distinct reaction pathways, leading to the formation of stable intermediates. Additionally, TC-SP 14 exhibits intriguing solvation dynamics, influencing its interaction with various substrates and altering reaction rates.