E2F-4 Antibody (D-3): sc-6851
- E2F-4 Antibody (D-3) is a mouse monoclonal IgG1 κ, cited in 8 publications, provided at 200 µg/ml
- raised against amino acids 108-300 of E2F-4 of human origin
- recommended for detection of E2F-4 of mouse, rat and human origin by WB, IP, IF and IHC(P)
- available conjugated to agarose for IP; and to HRP for WB, IHC(P) and ELISA
- TransCruz reagent for Gel Supershift and ChIP applications (sc-6851 X, 200 µg/0.1 ml)
- See E2F-4 (D-7): sc-398543 for E2F-4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for E2F-4 Antibody (D-3) for WB and IHC(P) applications. These reagents are now offered in bundles with E2F-4 Antibody (D-3) (see ordering information below).
E2F-4 Antibody (D-3) is a mouse monoclonal IgG1 antibody that detects E2F-4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry (IHC). E2F-4 plays a crucial role in regulating the cell cycle, particularly in the transition from the G1 phase to the S phase, by controlling the expression of genes necessary for DNA synthesis and cell proliferation. This regulation is vital for maintaining proper cell growth and division, as dysregulation of E2F-4 can lead to uncontrolled cell proliferation and is often implicated in various cancers. E2F-4 interacts with the retinoblastoma protein (Rb) to form a transcriptional regulatory complex that is essential for the precise control of cell cycle progression. Formation of heterodimers with the DP-1 protein enhances E2F-4 transcriptional activity, thereby influencing the expression of target genes that are critical for cell cycle advancement. E2F-4 (D-3) antibody enables researchers to gain insights into the mechanisms of cell cycle regulation and the potential implications of E2F-4 in oncogenesis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
E2F-4 Antibody (D-3) | sc-6851 | 200 µg/ml | $322.00 | |||
E2F-4 Antibody (D-3): m-IgG Fc BP-HRP Bundle | sc-536550 | 200 µg Ab; 10 µg BP | $361.00 | |||
E2F-4 Antibody (D-3): m-IgGκ BP-HRP Bundle | sc-533701 | 200 µg Ab; 40 µg BP | $361.00 | |||
E2F-4 Antibody (D-3): m-IgG1 BP-HRP Bundle | sc-544669 | 200 µg Ab; 20 µg BP | $361.00 | |||
E2F-4 Antibody (D-3) AC | sc-6851 AC | 500 µg/ml, 25% agarose | $424.00 | |||
E2F-4 Antibody (D-3) HRP | sc-6851 HRP | 200 µg/ml | $322.00 | |||
E2F-4 Antibody (D-3) X | sc-6851 X | 200 µg/0.1 ml | $322.00 |