Dynamin I/II Antibody (E-4): sc-390160
- Dynamin I/II Antibody (E-4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against a peptide mapping at the N-terminus of Dynamin II of human origin
- recommended for detection of Dynamin I and Dynamin II of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine and bovine
- See Dynamin II (G-4): sc-166669 for Dynamin I/II antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Dynamin I/II Antibody (E-4) for WB applications. These reagents are now offered in bundles with Dynamin I/II Antibody (E-4) (see ordering information below).
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Dynamin I/II Antibody (E-4) is a mouse monoclonal IgG1 antibody that detects Dynamin I and Dynamin II in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Dynamin I and II are critical members of the dynamin family, functioning as GTPase and microtubule-associated proteins that play essential roles in endocytosis, synaptic transmission, and neurogenesis. Dynamin I is predominantly localized in the central nervous system, while Dynamin II is widely distributed throughout various tissues, with the highest expression levels found in the testis. The structure of Dynamin I and II includes SH3 and proline-rich domains, which are vital for mediating interactions with various effectors that regulate GTPase activity. These interactions facilitate the recruitment of Dynamin I to clathrin-coated pits through SH3 domain interactions with amphiphysin, a protein highly expressed in the brain. Understanding the structural features and functional interactions of Dynamin I and II is important for elucidating their roles in cellular processes and potential implications in neurological disorders. Anti-Dynamin I/II antibody (E-4) is an invaluable tool for researchers investigating these dynamic proteins and their contributions to cellular mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dynamin I/II Antibody (E-4) | sc-390160 | 200 µg/ml | $322.00 | |||
Dynamin I/II Antibody (E-4): m-IgG Fc BP-HRP Bundle | sc-538063 | 200 µg Ab; 10 µg BP | $361.00 | |||
Dynamin I/II Antibody (E-4): m-IgGκ BP-HRP Bundle | sc-535591 | 200 µg Ab; 40 µg BP | $361.00 | |||
Dynamin I/II Antibody (E-4): m-IgG1 BP-HRP Bundle | sc-545507 | 200 µg Ab; 20 µg BP | $361.00 | |||
Dynamin I/II (E-4) Neutralizing Peptide | sc-390160 P | 100 µg/0.5 ml | $69.00 |