DNA pol µ Antibody (C-1): sc-515349
- DNA pol µ Antibody (C-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 245-320 mapping within an internal region of DNA pol µ of human origin
- recommended for detection of DNA pol µ of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for DNA pol µ Antibody (C-1) for WB applications. These reagents are now offered in bundles with DNA pol µ Antibody (C-1) (see ordering information below).
QUICK LINKS
SEE ALSO...
DNA pol µ Antibody (C-1) is a mouse monoclonal IgG1 antibody that detects DNA polymerase µ (DNA pol µ) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DNA pol µ plays a crucial role in the repair of double-stranded breaks in DNA, particularly through a mechanism known as microhomology-mediated end joining. DNA pol µ is unique among DNA polymerases due to its ability to incorporate both deoxynucleotides and ribonucleotides in a template-directed manner, which suggests a novel function in DNA repair processes that may be critical for maintaining genomic stability. The incorporation of ribonucleotides can lead to the formation of RNA-DNA hybrids, which are important for various cellular processes, including the regulation of gene expression and the response to DNA damage. Anti-DNA pol µ antibody (C-1) enables researchers to gain insights into the dynamics of DNA repair mechanisms and the potential implications of ribonucleotide incorporation in cellular health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DNA pol µ Antibody (C-1) | sc-515349 | 200 µg/ml | $322.00 | |||
DNA pol μ Antibody (C-1): m-IgG Fc BP-HRP Bundle | sc-538776 | 200 µg Ab; 10 µg BP | $361.00 | |||
DNA pol μ Antibody (C-1): m-IgGκ BP-HRP Bundle | sc-536446 | 200 µg Ab; 40 µg BP | $361.00 | |||
DNA pol μ Antibody (C-1): m-IgG1 BP-HRP Bundle | sc-545875 | 200 µg Ab; 20 µg BP | $361.00 |