DNA pol ε A Antibody (D-10): sc-390785

DNA pol ε A Antibody (D-10) is a mouse monoclonal IgG2a kappa light chain antibody that detects DNA pol epsilon A protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DNA pol epsilon A (D-10) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. DNA pol epsilon A protein plays a crucial role in DNA replication, particularly in the synthesis of the leading strand, and is essential for maintaining genome stability. DNA pol epsilon A is a multi-subunit enzyme, with the catalytic subunit encoded by the POL2 gene, and proper function is vital for accurate duplication of genetic material during cell division. DNA pol epsilon A′s structure, which includes a unique arrangement of subunits, allows for high-fidelity DNA synthesis and proofreading capabilities, ensuring error correction during replication. This structural integrity is critical, as dysfunction can lead to genomic instability and contribute to various diseases, including cancer. Using anti-DNA pol epsilon A antibody (D-10) in research can provide valuable insights into DNA replication and repair mechanisms, furthering understanding of cellular processes and their implications in health and disease.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-DNA pol ε A Antibody (D-10) has 3 citations in a variety of scientific publications.

Primary antibodies like Anti-DNA pol ε A Antibody (D-10) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

DNA pol ε A Antibody (D-10) Specifications

Alternate Product Name: DNA pol ε A

Product Clone Name: D-10

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 1-300

Epitope Target: DNA pol ε A

Epitope Species: human

Product Reactivity/Detection: DNA pol ε A

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for DNA pol ε A Antibody (D-10): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred DNA pol ε A antibody is DNA pol ε A Antibody (3C5.1): sc-12728.