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Cytokeratin 7/17 Antibody (C46): sc-8421

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Datasheets
  • Cytokeratin 7/17 Antibody (C46) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
  • raised against a Cytoskeleton preparation from HeLa cells
  • recommended for detection of Cytokeratin 7 and Cytokeratin 17 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • See Cytokeratin 7 (RCK105): sc-23876 for Cytokeratin 7/17 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Cytokeratin 7/17 Antibody (C46) for WB and IHC(P) applications. These reagents are now offered in bundles with Cytokeratin 7/17 Antibody (C46) (see ordering information below).

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Cytokeratin 7/17 Antibody (C46) is a mouse monoclonal IgG1 kappa light chain antibody engineered to simultaneously detect Cytokeratin 7 (KRT7) and Cytokeratin 17 (KRT17), also known as sarcolectin and keratin 17, respectively. Anti-Cytokeratin 7/17 antibody (C46) is raised against a cytoskeleton preparation from HeLa cells, ensuring precise targeting of its epitopes. Cytokeratin 7/17 monoclonal antibody (C46) exhibits broad species reactivity, including mouse, rat, and human, and is compatible with multiple applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Cytokeratin 7 plays a vital role in maintaining the structural integrity and function of epithelial cells, particularly in the differentiation and specialization of tissues like the pancreatic ducts and islets of Langerhans. Meanwhile, Cytokeratin 17 is essential for the resilience and repair of basal epithelial cells, serving as a key marker for basal cell differentiation and associated with various hyperproliferative disorders and cancers. Cytokeratin 7/17 (C46) monoclonal antibody allows researchers to study the interplay between these proteins in epithelial biology and pathology, facilitating the identification and characterization of different tumor types. Anti-Cytokeratin 7/17 antibody (C46) provides comprehensive insights into epithelial cell dynamics, making this tool invaluable for research in cell biology, pathology, and oncology.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cytokeratin 7/17 Antibody (C46)

sc-8421
200 µg/ml
$316.00

Cytokeratin 7/17 Antibody (C46): m-IgG Fc BP-HRP Bundle

sc-536563
200 µg Ab; 10 µg BP
$354.00

Cytokeratin 7/17 Antibody (C46): m-IgGκ BP-HRP Bundle

sc-533714
200 µg Ab; 40 µg BP
$354.00

Cytokeratin 7/17 Antibody (C46): m-IgG1 BP-HRP Bundle

sc-544677
200 µg Ab; 20 µg BP
$354.00

What is the recommended fixation method for immunofluorescence staining with Cytokeratin 7/17 (C46): sc-8421 monoclonal antibody?

Asked by: Randy McDonald
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-02-25
  • y_2025, m_12, d_14, h_10CST
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Rated 4 out of 5 by from Good Western blot data in AGood Western blot data in A-431 and ME-180 whole cell lysates. -SCBT QC
Date published: 2015-04-11
Rated 5 out of 5 by from Great data with immunoGreat data with immuno-peroxidase staining of formalin-fixed, paraffin-embedded human liver tumor samples. -SCBT QC
Date published: 2015-02-07
Rated 5 out of 5 by from Good IF data obtained in HeLa samplesGood IF data obtained in HeLa samples. -SCBT QC
Date published: 2015-01-26
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Cytokeratin 7/17 Antibody (C46) is rated 4.7 out of 5 by 3.
  • y_2025, m_12, d_14, h_10
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