QUICK LINKS
SEE ALSO...
Cytokeratin 14 Antibody (RCK107) is a mouse monoclonal IgG1 antibody that detects Cytokeratin 14 in mouse, rat, human, porcine, and canine samples through applications such as western blotting (WB) and immunofluorescence (IF). Cytokeratin 14 is a vital component of the cytoskeletal structure in epithelial cells, primarily found in the basal layer of the epidermis, where Cytokeratin 14 plays a crucial role in maintaining cellular integrity and resilience against mechanical stress. Cytokeratin 14 forms heterodimers with other cytokeratins, contributing to the formation of intermediate filaments that provide structural support to keratinocytes. Proper functioning of Cytokeratin 14 is essential for skin health, as mutations in the gene encoding Cytokeratin 14 can lead to epidermolysis bullosa simplex, a genetic disorder characterized by fragile skin that blisters easily. Expression of Cytokeratin 14 is also significant in various skin diseases, including Bowen′s disease, where distinct expression patterns can aid in diagnosis and characterization of malignant tumors. Anti-Cytokeratin 14 antibody (RCK107) serves as an invaluable tool for researchers studying epithelial cell biology, skin disorders, and cancer pathology, allowing detailed analysis in various species.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytokeratin 14 Antibody (RCK107) | sc-23878 | 200 µg/ml | $316.00 | |||
Cytokeratin 14 Antibody (RCK107): m-IgG Fc BP-HRP Bundle | sc-536682 | 200 µg Ab; 10 µg BP | $354.00 | |||
Cytokeratin 14 Antibody (RCK107): m-IgGκ BP-HRP Bundle | sc-533841 | 200 µg Ab; 40 µg BP | $354.00 | |||
Cytokeratin 14 Antibody (RCK107): m-IgG1 BP-HRP Bundle | sc-544762 | 200 µg Ab; 20 µg BP | $354.00 |