cyclin A Antibody (E72.1): sc-53232
- cyclin A Antibody (E72.1) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against bovine cyclin A
- recommended for detection of cyclin A of mouse, rat and human origin by WB, IP and IF; also reactive with additional species, including bovine
- See cyclin A (B-8): sc-271682 for cyclin A antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for cyclin A Antibody (E72.1) for WB applications. These reagents are now offered in bundles with cyclin A Antibody (E72.1) (see ordering information below).
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Cyclin A Antibody (E72.1) is a mouse monoclonal IgG1 antibody that detects cyclin A in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Cyclin A plays a pivotal role in regulating the eukaryotic cell cycle, particularly during S phase, where cyclin A is crucial for proper DNA replication progression. Cyclin A is primarily located in the nucleus, where cyclin A associates with cyclin-dependent kinase-2 (Cdk2) to form active complexes driving cell cycle transitions. Nuclear localization of cyclin A ensures precise cell cycle machinery regulation, preventing uncontrolled cell division that can lead to tumorigenesis. Cyclin A has been implicated in various cellular processes, including cell transformation, and interacts with key regulatory proteins such as E1A, transcription factors DRTF1 and E2F, and retinoblastoma protein, p110. Anti-cyclin A antibody (E72.1) serves as an essential tool for researchers studying cell cycle dynamics and molecular mechanisms underlying cell proliferation and cancer.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cyclin A Antibody (E72.1) | sc-53232 | 200 µg/ml | $322.00 | |||
cyclin A Antibody (E72.1): m-IgG Fc BP-HRP Bundle | sc-536912 | 200 µg Ab; 10 µg BP | $361.00 | |||
cyclin A Antibody (E72.1): m-IgGκ BP-HRP Bundle | sc-534085 | 200 µg Ab; 40 µg BP | $361.00 | |||
cyclin A Antibody (E72.1): m-IgG1 BP-HRP Bundle | sc-544893 | 200 µg Ab; 20 µg BP | $361.00 |