Anti-cyclin A Antibody (B-8) is a mouse monoclonal IgG2a κ cyclin A antibody, cited in 71 publications, provided at 200 µg/ml
raised against amino acids 1-432 representing full length cyclin A of human origin
cyclin A Antibody (B-8) is recommended for detection of cyclin A and cyclin A1 of human origin by WB, IP, IF, IHC(P) and ELISA
Anti-cyclin A Antibody (B-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
TransCruz reagent for ChIP application (sc-271682 X, 200 µg/0.1 ml)
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of cyclin A (B-8): sc-271682.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for cyclin A Antibody (B-8) for WB and IHC(P) applications. These reagents are now offered in bundles with cyclin A Antibody (B-8) (see ordering information below).
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
cyclin A Antibody (B-8) is a high quality monoclonal cyclin A antibody (also designated CCNA2 antibody) suitable for the detection of the cyclin A protein of human origin. cyclin A Antibody (B-8) is available as both the non-conjugated anti-cyclin A antibody form, as well as multiple conjugated forms of anti-cyclin A antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. The best-characterized cyclin complex is the mitotic cyclin B/Cdc2 p34 kinase, the active component of maturing promoting factor. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin- dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F and retinoblastoma protein, p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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