CPSF2 Antibody (A-6): sc-398539
- CPSF2 Antibody (A-6) is a mouse monoclonal mouse IgG2b κ κ provided at 200 µg/ml
- raised against amino acids 194-493 mapping within an internal region of CPSF2 of human origin
- recommended for detection of CPSF2 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CPSF2 Antibody (A-6) for WB applications. These reagents are now offered in bundles with CPSF2 Antibody (A-6) (see ordering information below).
CPSF2 Antibody (A-6) is a mouse monoclonal IgG2b antibody that detects CPSF2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CPSF2 plays a crucial role in the processing of eukaryotic mRNAs, specifically in the cleavage and polyadenylation of pre-mRNA, which is essential for the stability and translation of mRNA molecules. CPSF2 is part of the cleavage and polyadenylation specificity factor complex, which is localized in the nucleoplasm and is responsible for recognizing the AAUAAA signal in pre-mRNA. This recognition is vital as it initiates the cleavage of the transcript and the addition of a poly(A) tail, processes that are critical for mRNA maturation and regulation of gene expression. CPSF2 interacts with various proteins, including U1 snRNP-A, which enhances the efficiency of polyadenylation by stabilizing the interaction between CPSF and AAUAAA-containing RNAs. The human CPSF2 gene is located on chromosome 14q32.12 and encodes the second largest subunit of the CPSF complex, underscoring its importance in the post-transcriptional regulation of gene expression. anti-CPSF2 antibody (A-6) is an invaluable tool for researchers studying mRNA processing and its implications in various biological processes and diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CPSF2 Antibody (A-6) | sc-398539 | 200 µg/ml | $316.00 | |||
CPSF2 Antibody (A-6): m-IgG Fc BP-HRP Bundle | sc-538467 | 200 µg Ab; 10 µg BP | $354.00 | |||
CPSF2 Antibody (A-6): m-IgGκ BP-HRP Bundle | sc-536089 | 200 µg Ab; 40 µg BP | $354.00 | |||
CPSF2 Antibody (A-6): m-IgG2b BP-HRP Bundle | sc-549951 | 200 µg Ab; 10 µg BP | $354.00 |