COL9A2 Antibody (H-8): sc-398130
- COL9A2 Antibody (H-8) is a mouse monoclonal IgG1 κ COL9A2 antibody, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 341-515 mapping within an internal region of Collagen α2 Type IX of human origin
- COL9A2 Antibody (H-8) is recommended for detection of Collagen α2 Type IX of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-COL9A2 Antibody (H-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for COL9A2 Antibody (H-8) for WB applications. These reagents are now offered in bundles with COL9A2 Antibody (H-8) (see ordering information below).
COL9A2 Antibody (H-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects COL9A2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). COL9A2 (H-8) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. COL9A2 protein, also known as collagen alpha-2(IX) chain, is a crucial component of the extracellular matrix, particularly in hyaline cartilage and the vitreous body of the eye. This 689 amino acid protein belongs to the fibril-associated collagens with interrupted helices (FACIT) family and plays a significant role in maintaining the structural integrity and resilience of cartilage, which is essential for joint function and mobility. Proper functioning of COL9A2 is vital, as mutations in the COL9A2 gene can lead to multiple epiphyseal dysplasia, a condition characterized by skeletal abnormalities. By utilizing anti-COL9A2 antibody (H-8) in your research, you can gain valuable insights into the role of this protein in connective tissue disorders and its potential implications in therapeutic strategies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
COL9A2 Antibody (H-8) References:
- Collagen and bone strength. | Boskey, AL., et al. 1999. J Bone Miner Res. 14: 330-5. PMID: 10027897
- An allele of COL9A2 associated with intervertebral disc disease. | Annunen, S., et al. 1999. Science. 285: 409-12. PMID: 10411504
- Review article: platelet-collagen interactions: membrane receptors and intracellular signalling pathways. | Alberio, L. and Dale, GL. 1999. Eur J Clin Invest. 29: 1066-76. PMID: 10583456
- A mutation in COL9A1 causes multiple epiphyseal dysplasia: further evidence for locus heterogeneity. | Czarny-Ratajczak, M., et al. 2001. Am J Hum Genet. 69: 969-80. PMID: 11565064
- Clinical phenotype and molecular diagnosis of multiple epiphyseal dysplasia with relative hip sparing during childhood (EDM2). | Fiedler, J., et al. 2002. Am J Med Genet. 112: 144-53. PMID: 12244547
- Double-layered patella in multiple epiphyseal dysplasia is not exclusive to DTDST mutation. | Nakashima, E., et al. 2005. Am J Med Genet A. 133A: 106-7. PMID: 15633184
- Cell adhesion to collagenous matrices. | McCarthy, JB., et al. 1996. Biopolymers. 40: 371-81. PMID: 8765608
- The cartilage collagens: a review of their structure, organization, and role in the pathogenesis of experimental arthritis in animals and in human rheumatic disease. | Cremer, MA., et al. 1998. J Mol Med (Berl). 76: 275-88. PMID: 9535561
- Human COL9A1 and COL9A2 genes. Two genes of 90 and 15 kb code for similar polypeptides of the same collagen molecule. | Pihlajamaa, T., et al. 1998. Matrix Biol. 17: 237-41. PMID: 9707347
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
COL9A2 Antibody (H-8) | sc-398130 | 200 µg/ml | $322.00 | |||
COL9A2 Antibody (H-8): m-IgG Fc BP-HRP Bundle | sc-527740 | 200 µg Ab; 10 µg BP | $361.00 | |||
COL9A2 Antibody (H-8): m-IgG1 BP-HRP Bundle | sc-533113 | 200 µg Ab; 20 µg BP | $361.00 | |||
COL9A2 Antibody (H-8) AC | sc-398130 AC | 500 µg/ml, 25% agarose | $424.00 | |||
COL9A2 Antibody (H-8) HRP | sc-398130 HRP | 200 µg/ml | $322.00 | |||
COL9A2 Antibody (H-8) FITC | sc-398130 FITC | 200 µg/ml | $336.00 | |||
COL9A2 Antibody (H-8) PE | sc-398130 PE | 200 µg/ml | $349.00 | |||
COL9A2 Antibody (H-8) Alexa Fluor® 488 | sc-398130 AF488 | 200 µg/ml | $364.00 | |||
COL9A2 Antibody (H-8) Alexa Fluor® 546 | sc-398130 AF546 | 200 µg/ml | $364.00 | |||
COL9A2 Antibody (H-8) Alexa Fluor® 594 | sc-398130 AF594 | 200 µg/ml | $364.00 | |||
COL9A2 Antibody (H-8) Alexa Fluor® 647 | sc-398130 AF647 | 200 µg/ml | $364.00 | |||
COL9A2 Antibody (H-8) Alexa Fluor® 680 | sc-398130 AF680 | 200 µg/ml | $364.00 | |||
COL9A2 Antibody (H-8) Alexa Fluor® 790 | sc-398130 AF790 | 200 µg/ml | $364.00 |