Date published: 2026-5-5

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COL2A1 Antibodies

Santa Cruz Biotechnology features a diverse variety of COL2A1 monoclonal antibodies for research in understanding collagen type II's role in various biological processes. COL2A1 monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Collagen type II, encoded by the COL2A1 gene, is a crucial structural component of cartilage and plays a significant role in maintaining the integrity and function of cartilage tissue. The COL2A1 gene is essential for the development and maintenance of skeletal tissues, and mutations in COL2A1 are associated with various skeletal disorders, including achondrogenesis and osteoarthritis. Understanding COL2A1 function is vital for advancing research in cartilage biology and related diseases. Research applications include studying cartilage development, investigating skeletal disorders, and exploring potential therapeutic approaches. COL2A1 expression patterns can be effectively monitored across different developmental stages and tissue types. Investigating COL2A1's role in disease progression helps identify new therapeutic targets. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing our understanding of cartilage biology and skeletal development.

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COL2A1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

COL2A1 Antibody (M2139)

sc-52658mouse IgG2b κ(m)WB, IP, IF, IHC(P)m, r, h
171
(18)

COL2A1 Antibody (1H1)

sc-517571mouse IgG(h)IF, IHC(P)m, r, h
1
(0)

COL2A1 Antibody (9F11)

sc-517573mouse IgG(h)IF, IHC(P)m, r, h

new

(0)

COL2A1 Antibody (B-1)

sc-518017mouse IgG1 κ814-838 (h)WB, IP, IF, IHC(P), ELISAm, r, h
7
(3)

COL2A1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

COL2A1 CRISPR/Cas9 KO Plasmid (h)

sc-400359hGene KnockoutGFP0
(0)

COL2A1 Double Nickase Plasmid (h)

sc-400359-NIChGene KnockoutPuromycin0
(0)

COL2A1 Double Nickase Plasmid (h2)

sc-400359-NIC-2hGene KnockoutPuromycin0
(0)

COL2A1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

COL2A1 CRISPR Activation Plasmid (h)

sc-400359-ACThGene ActivationPuro, Blast, Hygro0
(0)

COL2A1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

COL2A1 siRNA (h)

sc-35081hGene SilencingN/A0
(0)

COL2A1 shRNA Plasmid (h)

sc-35081-SHhGene SilencingPuromycin0
(0)

COL2A1 shRNA (h) Lentiviral Particles

sc-35081-VhGene SilencingPuromycin0
(0)

COL2A1 siRNA (m)

sc-35082mGene SilencingN/A0
(0)

COL2A1 shRNA Plasmid (m)

sc-35082-SHmGene SilencingPuromycin0
(0)

COL2A1 shRNA (m) Lentiviral Particles

sc-35082-VmGene SilencingPuromycin0
(0)