COL10A1 Antibodies

Santa Cruz Biotechnology delivers a wide array of COL10A1 monoclonal antibodies for investigating collagen type X in various biological processes. COL10A1 monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). COL10A1, or collagen type X, is primarily expressed in hypertrophic cartilage and plays a crucial role in endochondral ossification, which is essential for bone development and growth. Expression of COL10A1 is tightly regulated during skeletal development, and abnormalities in COL10A1 can lead to various skeletal disorders. Understanding COL10A1 function is vital for elucidating the mechanisms underlying cartilage and bone diseases. Research has shown that COL10A1 mutations are associated with several inherited skeletal dysplasias, including Schmid metaphyseal chondrodysplasia. COL10A1 also serves as a marker for chondrocyte hypertrophy and cartilage mineralization. Investigating COL10A1 expression patterns helps reveal key insights into skeletal development and repair mechanisms. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of skeletal biology and contribute to the development of therapeutic strategies for bone and cartilage disorders.