Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US, Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been receivedPlease note: We can not ship to PO boxes
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal health products, bulky and/or heavy items
Collagens (COLs) are fibrous, extracellular matrix proteins with high tensile strength that function as the major components of connective tissue, such as tendons and cartilage. All COL proteins contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. There are several types of COL proteins, including fibril-forming interstitial COLs (types I, II, III and V), basement membrane COLs (type IV) and beaded filament COLs (type VI). COL6A3 (Collagen alpha-3(VI) chain), is a 3,176 amino acid secreted protein that contains one fibronectin type-III domain, one MPTI inhibitor domain and 12 VWFA domains and functions as the third (and largest) of three alpha chains of the type VI COL protein complex. Existing as a trimer with two other type VI alpha proteins, COL6A3 acts as a cell-binding protein that plays an important role in the organization of matrix components. Defects in the gene encoding COL6A3 are the cause of Bethlem myopathy (BM), a rare autosomal proximal myopathy, and Ullrich congenital muscular dystrophy (UCMD), an autosomal recessive congenital myopathy. Multiple isoforms of COL6A3 exist due to alternative splicing events.