COL6A3 Antibody (A-5) is a mouse monoclonal IgG1 (kappa light chain) provided at 200 µg/ml
raised against amino acids 301-600 mapping within an internal region of Collagen α3 Type VI of human origin
COL6A3 Antibody (A-5) is recommended for detection of Collagen α3 Type VI isoforms 1 and 2 of human origin by WB, IP, IF and ELISA
COL6A3 Antibody (A-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of COL6A3 (A-5): sc-515335.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Collagens (COLs) are fibrous, extracellular matrix proteins with high tensile strength that function as the major components of connective tissue, such as tendons and cartilage. All COL proteins contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. There are several types of COL proteins, including fibril-forming interstitial COLs (types I, II, III and V), basement membrane COLs (type IV) and beaded filament COLs (type VI). COL6A3 (Collagen alpha-3(VI) chain), is a 3,176 amino acid secreted protein that contains one fibronectin type-III domain, one MPTI inhibitor domain and 12 VWFA domains and functions as the third (and largest) of three alpha chains of the type VI COL protein complex. Existing as a trimer with two other type VI alpha proteins, COL6A3 acts as a cell-binding protein that plays an important role in the organization of matrix components. Defects in the gene encoding COL6A3 are the cause of Bethlem myopathy (BM), a rare autosomal proximal myopathy, and Ullrich congenital muscular dystrophy (UCMD), an autosomal recessive congenital myopathy. Multiple isoforms of COL6A3 exist due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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