COL6A1 Antibody (F-8): sc-398976
- COL6A1 Antibody (F-8) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 51-250 mapping near the N-terminus of Collagen α1 Type VI of human origin
- recommended for detection of Collagen α1 Type VI of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for COL6A1 Antibody (F-8) for WB applications. These reagents are now offered in bundles with COL6A1 Antibody (F-8) (see ordering information below).
COL6A1 Antibody (F-8) is a mouse monoclonal IgG2a antibody that detects COL6A1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). COL6A1 is a crucial component of type VI collagen, which is primarily located in the extracellular matrix and plays a significant role in maintaining tissue integrity and structure. COL6A1 is essential for the formation of a network that supports cell adhesion and regulates cellular behavior, which is vital for normal tissue function and repair processes. COL6A1′s presence in various tissues, including muscle and skin, highlights COL6A1′s importance in connective tissue organization and involvement in pathological conditions such as muscular dystrophies and fibrosis. Anti-COL6A1 antibody (F-8) helps researchers gain insights into COL6A1′s role in health and disease, making anti-COL6A1 antibody (F-8) an invaluable tool for studies focused on connective tissue disorders and cellular interactions within the extracellular matrix.
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COL6A1 Antibody (F-8) References:
- COL6A1 polymorphisms associated with ossification of the ligamentum flavum and ossification of the posterior longitudinal ligament. | Kong, Q., et al. 2007. Spine (Phila Pa 1976). 32: 2834-8. PMID: 18246005
- Reactive stroma component COL6A1 is upregulated in castration-resistant prostate cancer and promotes tumor growth. | Zhu, YP., et al. 2015. Oncotarget. 6: 14488-96. PMID: 25895032
- Upregulation of COL6A1 is predictive of poor prognosis in clear cell renal cell carcinoma patients. | Wan, F., et al. 2015. Oncotarget. 6: 27378-87. PMID: 26317545
- Expression of COL6A1 predicts prognosis in cervical cancer patients. | Hou, T., et al. 2016. Am J Transl Res. 8: 2838-44. PMID: 27398167
- COL6A1 promotes metastasis and predicts poor prognosis in patients with pancreatic cancer. | Owusu-Ansah, KG., et al. 2019. Int J Oncol. 55: 391-404. PMID: 31268154
- Col6a1+/CD201+ mesenchymal cells regulate intestinal morphogenesis and homeostasis. | Melissari, MT., et al. 2021. Cell Mol Life Sci. 79: 1. PMID: 34910257
- P4HA1 Regulates CD31 via COL6A1 in the Transition of Glioblastoma Stem-Like Cells to Tumor Endothelioid Cells. | Han, X., et al. 2022. Front Oncol. 12: 836511. PMID: 35494018
- Exon-Skipping for a Pathogenic COL6A1 Variant in Ullrich Congenital Muscular Dystrophy. | Aguti, S., et al. 2023. Methods Mol Biol. 2587: 387-407. PMID: 36401040
- High expression of COL6A1 predicts poor prognosis and response to immunotherapy in bladder cancer. | Zhang, X., et al. 2023. Cell Cycle. 22: 610-618. PMID: 36474424
- COL6A1 Inhibits the Malignant Development of Bladder Cancer by Regulating FBN1. | Yang, T., et al. 2024. Cell Biochem Biophys.. PMID: 39365515
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
COL6A1 Antibody (F-8) | sc-398976 | 200 µg/ml | $316.00 | |||
COL6A1 Antibody (F-8): m-IgG Fc BP-HRP Bundle | sc-538555 | 200 µg Ab; 10 µg BP | $354.00 | |||
COL6A1 Antibody (F-8): m-IgGκ BP-HRP Bundle | sc-536193 | 200 µg Ab; 40 µg BP | $354.00 |