CLAMP Antibody (E-9): sc-374099
- CLAMP Antibody (E-9) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 41-73 within an internal region of CLAMP of human origin
- recommended for detection of CLAMP of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CLAMP Antibody (E-9) for WB and IHC(P) applications. These reagents are now offered in bundles with CLAMP Antibody (E-9) (see ordering information below).
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SEE ALSO...
CLAMP Antibody (E-9) is a mouse monoclonal IgG2b antibody that detects CLAMP in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). CLAMP, also known as sperm flagellar protein 1 (SPEF1), is a 236 amino acid protein predominantly found in epididymal sperm, where CLAMP localizes to cell projections and the cytoplasm, playing a crucial role in microtubule organization. This microtubule-associated protein is essential for maintaining the structural integrity of the sperm flagellum, which is vital for sperm motility and fertility. CLAMP presence in other tissues such as the lung and brain suggests additional functions beyond reproduction, potentially influencing cellular processes in these organs. Notably, human CLAMP exists in two alternatively spliced isoforms, indicating a level of functional diversity that may be important for its roles in different tissues. The CLAMP gene is located on human chromosome 20, a region that contains over 600 genes and represents nearly 2% of the human genome, highlighting CLAMP′s evolutionary significance and potential involvement in various biological pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CLAMP Antibody (E-9) | sc-374099 | 200 µg/ml | $322.00 | |||
CLAMP Antibody (E-9): m-IgGκ BP-HRP Bundle | sc-535382 | 200 µg Ab; 40 µg BP | $361.00 | |||
CLAMP Antibody (E-9): m-IgG2b BP-HRP Bundle | sc-549404 | 200 µg Ab; 10 µg BP | $361.00 | |||
CLAMP (E-9) Neutralizing Peptide | sc-374099 P | 100 µg/0.5 ml | $69.00 |