Chk2 Antibody (B-4): sc-17748
- Chk2 Antibody (B-4) is a mouse monoclonal IgG1 κ, cited in 27 publications, provided at 200 µg/ml
- raised against amino acids 1-300 of Chk2 of human origin
- recommended for detection of Chk2 of human origin by WB, IP, IF, IHC(P) and ELISA
- See Chk2 (A-11): sc-17747 for Chk2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Chk2 Antibody (B-4) for WB and IHC(P) applications. These reagents are now offered in bundles with Chk2 Antibody (B-4) (see ordering information below).
QUICK LINKS
Chk2 Antibody (B-4) is a mouse monoclonal IgG1 antibody that detects Chk2 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry (IHC), and enzyme-linked immunosorbent assay (ELISA). Chk2 plays a critical role in maintaining genomic stability by acting as a key regulator in the DNA damage response pathway. Upon DNA damage, Chk2 is activated and phosphorylates several downstream targets, including Cdc25C, which leads to cell cycle arrest and allows for DNA repair mechanisms to take place. This function is vital for preventing the propagation of damaged DNA, thereby reducing the risk of mutations that could lead to cancer. Chk2 (B-4) monoclonal antibody is an essential tool for researchers studying the intricate mechanisms of cell cycle regulation and the cellular response to DNA damage.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Chk2 Antibody (B-4) | sc-17748 | 200 µg/ml | $322.00 | |||
Chk2 Antibody (B-4): m-IgG Fc BP-HRP Bundle | sc-536583 | 200 µg Ab; 10 µg BP | $361.00 | |||
Chk2 Antibody (B-4): m-IgGκ BP-HRP Bundle | sc-533734 | 200 µg Ab; 40 µg BP | $361.00 | |||
Chk2 Antibody (B-4): m-IgG1 BP-HRP Bundle | sc-544691 | 200 µg Ab; 20 µg BP | $361.00 |