Date published: 2026-4-23

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Chk2 Antibodies

Santa Cruz Biotechnology features a diverse variety of Chk2 monoclonal antibodies for research in cell cycle regulation and DNA damage response. Chk2 Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Checkpoint kinase 2 (Chk2) plays a critical role in the cellular response to DNA damage, acting as a key regulator in the activation of cell cycle checkpoints and apoptosis. By phosphorylating target proteins, Chk2 helps maintain genomic stability and prevent the propagation of damaged DNA, making it essential for cancer research and therapeutic development. Understanding the function of Chk2 is crucial for elucidating the mechanisms of tumorigenesis and developing targeted cancer therapies. Chk2 monoclonal antibodies enable precise detection and analysis of protein expression, localization, and interactions in various experimental settings. Researchers can explore DNA damage response pathways and cell cycle control mechanisms with high specificity and reliability. Santa Cruz Biotechnology monoclonal antibodies support scientists in advancing cancer research and therapeutic discoveries.

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Chk2 Antibodies

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Chk2 Antibody (A-11)

sc-17747mouse IgG1 κ1-300 (h)WB, IP, IF, ELISAm, r, h
49
(16)

Chk2 Antibody (A-12)

sc-5278mouse IgG2b κ1-300 (h)WB, IP, IF, IHC(P), FCM, ELISAm, r, h
76
(13)

Chk2 Antibody (B-4)

sc-17748mouse IgG1 κ1-300 (h)WB, IP, IF, IHC(P), ELISAh
27
(5)

Chk2 Antibody (DCS-270)

sc-56296mouse IgG2a κ(h)WB, IP, IF, IHC(P)h
14
(6)

Chk2 Antibody (DCS-273)

sc-56297mouse IgG1 κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(4)

Chk2 Antibody (19)

sc-136251mouse IgG131-234 (m)WB, IP, IFm, r, h
3
(3)

Chk2 CRISPR Knockout, HDR and Double Nickase Plasmids

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Chk2 CRISPR/Cas9 KO Plasmid (h)

sc-400438hGene KnockoutGFP
1
(0)

Chk2 HDR Plasmid (h)

sc-400438-HDRhHomology Directed RepairPuromycin
1
(0)

Chk2 Double Nickase Plasmid (h)

sc-400438-NIChGene KnockoutPuromycin
1
(0)

Chk2 Double Nickase Plasmid (h2)

sc-400438-NIC-2hGene KnockoutPuromycin
1
(0)

Chk2 CRISPR/Cas9 KO Plasmid (m)

sc-424521mGene KnockoutGFP0
(0)

Chk2 CRISPR Activation Products

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Chk2 CRISPR Activation Plasmid (h)

sc-400438-ACThGene ActivationPuro, Blast, Hygro
1
(0)

Chk2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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Chk2 siRNA (h)

sc-29271hGene SilencingN/A
17
(0)

Chk2 shRNA Plasmid (h)

sc-29271-SHhGene SilencingPuromycin
17
(0)

Chk2 shRNA (h) Lentiviral Particles

sc-29271-VhGene SilencingPuromycin
17
(0)

Chk2 siRNA (m)

sc-29272mGene SilencingN/A0
(0)

Chk2 shRNA Plasmid (m)

sc-29272-SHmGene SilencingPuromycin0
(0)

Chk2 shRNA (m) Lentiviral Particles

sc-29272-VmGene SilencingPuromycin0
(0)