CEACAM1 Antibody (6D305): sc-70450

CEACAM1 Antibody (6D305) is a mouse monoclonal IgG1 antibody that detects CEACAM1 in human samples through immunofluorescence (IF) and flow cytometry (FCM) applications. CEACAM1, also known as carcinoembryonic antigen-related cell adhesion molecule 1, is a 526 amino acid protein that exists in seven alternatively spliced isoforms, some of which are membrane-bound while others are secreted. Anti-CEACAM1 antibody (6D305) targets a protein that plays a crucial role in various cellular processes, including angiogenesis, apoptosis, and the organization of tissue architecture, as well as the modulation of both innate and adaptive immune responses. Notably, CEACAM1 is underexpressed in colorectal cancers, indicating its potential function as a tumor suppressor. The presence of one immunoglobulin-like V-type domain and three C2-type domains in CEACAM1 contributes to its structural complexity and functional versatility, making CEACAM1 an important target for research in cancer biology and immunology. CEACAM1 monoclonal antibody (6D305) is an essential tool for scientists investigating CEACAM1′s role in health and disease, providing valuable insights into its involvement in tumor suppression and immune regulation.

The preferred CEACAM1/2 antibody is CEACAM1/2 Antibody (E-12): sc-365126.