
CD47 Antibody (CC2C6) is a mouse monoclonal IgG1 antibody that detects CD47 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). CD47 is a crucial integral membrane protein that serves as a key regulator of cell signaling and communication, particularly in the context of immune response and cell adhesion. CD47 functions primarily as a "don′t eat me" signal, preventing phagocytosis by macrophages, which is vital for maintaining the survival of healthy cells and preventing premature elimination of erythrocytes. CD47′s importance is underscored by its role in various physiological processes, including the modulation of intracellular calcium levels upon cell adhesion to the extracellular matrix, which is essential for cellular responses to environmental cues. Additionally, CD47 interacts with thrombospondin, influencing cell adhesion and migration, and is expressed in a variety of cell types, including hemopoietic, epithelial, endothelial, and fibroblast cells, with particularly high expression in brain and mesenchymal cells. Anti-CD47 antibody (CC2C6) is an invaluable tool for researchers studying the intricate mechanisms of cell signaling and immune regulation, providing insights into potential therapeutic targets for diseases where CD47 is implicated.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD47 Antibody (CC2C6) | sc-21786 | 200 µg/ml | $322.00 | |||
CD47 Antibody (CC2C6): m-IgG Fc BP-HRP Bundle | sc-536675 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD47 Antibody (CC2C6): m-IgGκ BP-HRP Bundle | sc-533834 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD47 Antibody (CC2C6): m-IgG1 BP-HRP Bundle | sc-544756 | 200 µg Ab; 20 µg BP | $361.00 | |||
CD47 Antibody (CC2C6) FITC | sc-21786 FITC | 200 µg/ml | $336.00 | |||
CD47 Antibody (CC2C6) PE | sc-21786 PE | 200 µg/ml | $349.00 |