CD47 Activators represent a specific category of chemical compounds recognized for their capacity to modulate the activity of cluster of differentiation 47 (CD47). This chemical class operates by interacting with and enhancing the signaling pathways associated with CD47, a transmembrane protein that plays a multifaceted role in cell adhesion, immune regulation, and cellular responses to phagocytosis. CD47 is acknowledged for its involvement in diverse biological processes, including self-recognition, tissue integrity, and immune evasion.
CD47 Activators exert their influence through specific molecular interactions that may amplify the downstream effects of CD47-mediated signaling, contributing to the fine-tuning of immune responses, cell-cell interactions, and cellular behaviors in various contexts. The intricate mechanisms through which CD47 Activators impact CD47-related pathways remain a focus of ongoing scientific exploration, offering insights into the complex interplay between cellular communication, immune surveillance, and tissue maintenance. The specific ways in which this chemical class engages with CD47 underscore its significance in unraveling the complexities of cell-matrix interactions and enhancing our understanding across various scientific domains.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $98.00 $171.00 $425.00 $1560.00 | 12 | |
LPS, a bacterial component, induces CD47 expression as part of the immune response to microbial products. | ||||||
LY 364947 | 396129-53-6 | sc-203122 sc-203122A | 5 mg 10 mg | $107.00 $156.00 | 4 | |
TGF-β induces CD47 expression in certain cell types, influencing immune interactions. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
ATRA, a differentiation-inducing agent, upregulates CD47 expression during cellular differentiation. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
Hydrogen peroxide (H2O2), a compound associated with oxidative stress, is implicated in CD47 expression regulation. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
5-Aza-2'-deoxycytidine, a DNA methyltransferase inhibitor, can affect DNA methylation and potentially influence CD47 expression levels. | ||||||