CD47 Antibody (BRIC 126): sc-59079
- CD47 Antibody (BRIC 126) is a mouse monoclonal IgG2b κ, cited in 8 publications, provided at 200 µg/ml
- raised against erythrocytes of human origin
- Anti-CD47 Antibody (BRIC 126) is recommended for detection of CD47 of human, bovine, porcine and canine origin by WB, IP, IF and FCM
- Anti-CD47 Antibody (BRIC 126) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for CD47 Antibody (BRIC 126) for WB applications. These reagents are now offered in bundles with CD47 Antibody (BRIC 126) (see ordering information below).
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CD47 Antibody (BRIC 126) is a mouse monoclonal IgG2b kappa light chain antibody that detects CD47 protein of human, bovine, porcine, and canine origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). CD47 Antibody (BRIC 126) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CD47 is an integral membrane protein that plays a crucial role in regulating cation fluxes across cell membranes, particularly influencing intracellular calcium concentrations during cell adhesion to the extracellular matrix. This function is vital for various cellular processes, including migration, proliferation, and survival, as CD47 helps cells respond appropriately to their environment. Additionally, CD47 serves as a receptor for the C-terminal cell-binding domain of thrombospondin, which is important for cell signaling and communication. Notably, CD47 is absent from Rh-null erythrocytes, yet CD47 significantly contributes to cell adhesion in non-erythroid cells and may prevent the premature elimination of erythrocytes. Furthermore, CD47 is expressed on a variety of cell types, including hemopoietic cells, epithelial cells, endothelial cells, and fibroblasts, with particularly strong expression in brain and mesenchymal cells, highlighting CD47′s importance in both normal physiology and potential pathological conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD47 Antibody (BRIC 126) | sc-59079 | 200 µg/ml | $322.00 | |||
CD47 Antibody (BRIC 126): m-IgG Fc BP-HRP Bundle | sc-525676 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD47 Antibody (BRIC 126): m-IgG2b BP-HRP Bundle | sc-549613 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD47 Antibody (BRIC 126) AC | sc-59079 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CD47 Antibody (BRIC 126) HRP | sc-59079 HRP | 200 µg/ml | $322.00 | |||
CD47 Antibody (BRIC 126) FITC | sc-59079 FITC | 200 µg/ml | $336.00 | |||
CD47 Antibody (BRIC 126) PE | sc-59079 PE | 200 µg/ml | $349.00 | |||
CD47 Antibody (BRIC 126) Alexa Fluor® 488 | sc-59079 AF488 | 200 µg/ml | $364.00 | |||
CD47 Antibody (BRIC 126) Alexa Fluor® 546 | sc-59079 AF546 | 200 µg/ml | $364.00 | |||
CD47 Antibody (BRIC 126) Alexa Fluor® 594 | sc-59079 AF594 | 200 µg/ml | $364.00 | |||
CD47 Antibody (BRIC 126) Alexa Fluor® 647 | sc-59079 AF647 | 200 µg/ml | $364.00 | |||
CD47 Antibody (BRIC 126) Alexa Fluor® 680 | sc-59079 AF680 | 200 µg/ml | $364.00 | |||
CD47 Antibody (BRIC 126) Alexa Fluor® 790 | sc-59079 AF790 | 200 µg/ml | $364.00 |