CD40 Antibody (G-12): sc-514493
- CD40 Antibody (G-12) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 242-259 within a C-terminal cytoplasmic domain of CD40 of human origin
- Anti-CD40 Antibody (G-12) is recommended for detection of precursor and mature CD40 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-CD40 Antibody (G-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD40 Antibody (G-12) for WB applications. These reagents are now offered in bundles with CD40 Antibody (G-12) (see ordering information below).
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CD40 Antibody (G-12) is a mouse monoclonal IgG2a kappa light chain antibody that detects the precursor and mature CD40 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CD40 (G-12) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CD40 protein plays a crucial role in the immune response, primarily by mediating communication between B cells and T helper cells. CD40 is located on the surface of B cells and interacts with CD40 ligand (CD40L) expressed on activated T cells, which is essential for B cell activation and differentiation. This interaction not only promotes B cell proliferation but also facilitates immunoglobulin class switching, allowing B cells to produce different types of antibodies, including IgE, which is vital for mounting an effective immune response against pathogens. CD40′s importance in immune regulation is underscored by involvement in various immunological processes, including memory B cell generation and maintenance of long-term antibody responses. Understanding CD40 function and signaling pathways is critical for developing therapeutic strategies targeting immune-related diseases, making anti-CD40 antibody (G-12) an invaluable tool for researchers studying B cell biology and immunology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD40 Antibody (G-12) | sc-514493 | 200 µg/ml | $316.00 | |||
CD40 Antibody (G-12): m-IgG Fc BP-HRP Bundle | sc-531145 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD40 Antibody (G-12): m-IgGκ BP-HRP Bundle | sc-524745 | 200 µg Ab, 40 µg BP | $354.00 | |||
CD40 Antibody (G-12): m-IgG2a BP-HRP Bundle | sc-547703 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD40 Antibody (G-12) AC | sc-514493 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CD40 Antibody (G-12) HRP | sc-514493 HRP | 200 µg/ml | $316.00 | |||
CD40 Antibody (G-12) FITC | sc-514493 FITC | 200 µg/ml | $330.00 | |||
CD40 Antibody (G-12) PE | sc-514493 PE | 200 µg/ml | $343.00 | |||
CD40 Antibody (G-12) Alexa Fluor® 488 | sc-514493 AF488 | 200 µg/ml | $357.00 | |||
CD40 Antibody (G-12) Alexa Fluor® 546 | sc-514493 AF546 | 200 µg/ml | $357.00 | |||
CD40 Antibody (G-12) Alexa Fluor® 594 | sc-514493 AF594 | 200 µg/ml | $357.00 | |||
CD40 Antibody (G-12) Alexa Fluor® 647 | sc-514493 AF647 | 200 µg/ml | $357.00 | |||
CD40 Antibody (G-12) Alexa Fluor® 680 | sc-514493 AF680 | 200 µg/ml | $357.00 | |||
CD40 Antibody (G-12) Alexa Fluor® 790 | sc-514493 AF790 | 200 µg/ml | $357.00 | |||
CD40 (G-12) Neutralizing Peptide | sc-514493 P | 100 µg/0.5 ml | $68.00 |