Date published: 2025-10-9

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CD40 Antibodies

Santa Cruz Biotechnology features a diverse variety of CD40 monoclonal antibodies for investigating CD40's role in immune response and cell signaling. CD40 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CD40 is a crucial co-stimulatory molecule found on the surface of B cells and other immune cells, playing a significant role in the activation and regulation of immune responses. CD40 drives B cell proliferation, differentiation, and antibody production, making it a key player in adaptive immunity. Dysregulation of CD40 signaling has been implicated in various autoimmune diseases and cancers, highlighting its importance as a therapeutic target. CD40 monoclonal antibodies enable detailed analysis of immune cell interactions and signaling pathways. Researchers worldwide rely on CD40 monoclonal antibodies to explore immune regulation mechanisms and develop potential therapeutic strategies. Santa Cruz Biotechnology monoclonal antibodies for CD40 continue to support breakthrough discoveries in immunology research and therapeutic development.

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CD40 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CD40 Antibody (H-10)

sc-13128mouse IgG2b κ74-193 (h)WB, IP, IF, IHC(P), ELISAh
18
(13)

CD40 Antibody (HM40-3)

sc-20010Armenian Hamster IgM(m)WB, IP, IF, IHC(P), FCMm, r
4
(3)

CD40 Antibody (G-12)

sc-514493mouse IgG2a κ242-259 (h)WB, IP, IF, ELISAm, r, h
1
(0)

CD40 Antibody (LOB-11)

sc-13528mouse IgG2a κ(h)WB, IP, IF, IHC(P), FCMh
9
(8)

CD40 Antibody (BE-1)

sc-65263mouse IgG1 κ(h)WB, IP, IF, FCMh
1
(1)

CD40 Antibody (EA-5)

sc-65264mouse IgG1 κ(h)WB, IP, IF, FCMh
3
(1)

CD40 Antibody (MAB89)

sc-59047mouse IgG1(h)FCMh
3
(1)

CD40 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD40 CRISPR/Cas9 KO Plasmid (h2)

sc-400524-KO-2hGene KnockoutGFP0
(0)

CD40 HDR Plasmid (h2)

sc-400524-HDR-2hHomology Directed RepairPuromycin0
(0)

CD40 Double Nickase Plasmid (h)

sc-400524-NIChGene KnockoutPuromycin0
(0)

CD40 Double Nickase Plasmid (h2)

sc-400524-NIC-2hGene KnockoutPuromycin0
(0)

CD40 CRISPR/Cas9 KO Plasmid (m)

sc-423444mGene KnockoutGFP0
(0)

CD40 HDR Plasmid (m)

sc-423444-HDRmHomology Directed RepairPuromycin0
(0)

CD40 Double Nickase Plasmid (m)

sc-423444-NICmGene KnockoutPuromycin0
(0)

CD40 Double Nickase Plasmid (m2)

sc-423444-NIC-2mGene KnockoutPuromycin0
(0)

CD40 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD40 CRISPR Activation Plasmid (h)

sc-400524-ACThGene ActivationPuro, Blast, Hygro0
(0)

CD40 CRISPR Activation Plasmid (h2)

sc-400524-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CD40 Lentiviral Activation Particles (h)

sc-400524-LAChGene ActivationPuro, Blast, Hygro0
(0)

CD40 Lentiviral Activation Particles (h2)

sc-400524-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

CD40 CRISPR Activation Plasmid (m)

sc-423444-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CD40 CRISPR Activation Plasmid (m2)

sc-423444-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CD40 Lentiviral Activation Particles (m)

sc-423444-LACmGene ActivationPuro, Blast, Hygro0
(0)

CD40 Lentiviral Activation Particles (m2)

sc-423444-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CD40 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CD40 siRNA (h)

sc-29250hGene SilencingN/A
6
(0)

CD40 shRNA Plasmid (h)

sc-29250-SHhGene SilencingPuromycin
6
(0)

CD40 shRNA (h) Lentiviral Particles

sc-29250-VhGene SilencingPuromycin
6
(0)

CD40 siRNA (m)

sc-29998mGene SilencingN/A0
(0)

CD40 shRNA Plasmid (m)

sc-29998-SHmGene SilencingPuromycin0
(0)

CD40 shRNA (m) Lentiviral Particles

sc-29998-VmGene SilencingPuromycin0
(0)