CD4 Antibody (MT310): sc-19641

CD4 Antibody (MT310) is a mouse monoclonal IgG1 kappa light chain antibody specifically designed to detect CD4, also known as T4 or Leu 3, across mouse, rat, and human species. Anti-CD4 antibody (MT310) is recommended for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM), making it an essential tool for a wide range of research applications. CD4 is a membrane-bound glycoprotein composed of four extracellular immunoglobulin-like domains, which are crucial for its role in the immune system. Structurally, the multiple domains facilitate CD4 binding to class II major histocompatibility complex (MHC) molecules, enhancing interaction between T cell receptor (TCR) and antigen-presenting cells. This interaction is vital for effective T cell activation and subsequent immune response against pathogens. Additionally, CD4′s structural configuration allows functioning as a primary receptor for human immunodeficiency virus (HIV), making CD4 a key target in studies of viral entry and immune system dysfunction. CD4 is predominantly expressed on T helper cells, cortical cells, mature medullary thymocytes, microglial cells, and dendritic cells, highlighting CD4′s importance in both adaptive and innate immune responses. CD4 monoclonal antibody (MT310) facilitates critical research in immunology, including investigations into autoimmune diseases, infectious diseases, and immunotherapy development. By providing precise detection of CD4 expression, CD4 (MT310) antibody supports advancements in understanding immune function and disease mechanisms, making this reagent indispensable for both basic and applied scientific studies.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CD4 Antibody (MT310) has 79 citations in a variety of scientific publications.

Primary antibodies like Anti-CD4 Antibody (MT310) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CD4 Antibody (MT310) Specifications

Alternate Product Name: CD4 molecule

Product Clone Name: MT310

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: CD4

Epitope Species: human

Product Reactivity/Detection: CD4

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), FCM

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 79 citations in various scientific publications

Available Conjugates/Forms for CD4 Antibody (MT310): AC: Agarose, AF405: Alexa Fluor^® 405, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, APC-Cy7: Allophycocyanin with Cyanin-7, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred CD4 antibody is CD4 Antibody (GK1.5): sc-13573.