CD34 Antibody (B-6): sc-74499
- CD34 Antibody (B-6) is a mouse monoclonal IgG1 κ, cited in 68 publications, provided at 200 µg/ml
- raised against amino acids 151-290 of CD34 of mouse origin
- Anti-CD34 Antibody (B-6) is recommended for detection of CD34 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-CD34 Antibody (B-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CD34 Antibody (B-6) for WB and IHC(P) applications. These reagents are now offered in bundles with CD34 Antibody (B-6) (see ordering information below).
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SEE ALSO...
CD34 Antibody (B-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects CD34 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). CD34 (B-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CD34 is a heavily glycosylated transmembrane glycoprotein that plays a crucial role in identifying and isolating hematopoietic stem and progenitor cells, as CD34 appears on their surface. CD34 expression marks the most primitive stem cells, which are essential for blood and immune system development. As stem cells differentiate into lineage-committed progenitors, CD34 expression gradually diminishes, making CD34 a valuable marker for tracking stem cell differentiation. CD34 appears on small-vessel endothelial cells and certain cells in fetal and adult nervous tissue, highlighting CD34 importance in both hematopoiesis and vascular biology. CD34 cytoplasmic domain contains consensus sites for phosphorylation by activated protein kinase C, as well as serine, threonine, and tyrosine phosphorylation sites, which are critical for mediating intracellular signaling pathways that influence cell adhesion and migration.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD34 Antibody (B-6) | sc-74499 | 200 µg/ml | $316.00 | |||
CD34 Antibody (B-6): m-IgG Fc BP-HRP Bundle | sc-527031 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD34 Antibody (B-6): m-IgG1 BP-HRP Bundle | sc-532404 | 200 µg Ab; 20 µg BP | $354.00 | |||
CD34 Antibody (B-6) AC | sc-74499 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CD34 Antibody (B-6) HRP | sc-74499 HRP | 200 µg/ml | $316.00 | |||
CD34 Antibody (B-6) FITC | sc-74499 FITC | 200 µg/ml | $330.00 | |||
CD34 Antibody (B-6) PE | sc-74499 PE | 200 µg/ml | $343.00 | |||
CD34 Antibody (B-6) Alexa Fluor® 488 | sc-74499 AF488 | 200 µg/ml | $357.00 | |||
CD34 Antibody (B-6) Alexa Fluor® 546 | sc-74499 AF546 | 200 µg/ml | $357.00 | |||
CD34 Antibody (B-6) Alexa Fluor® 594 | sc-74499 AF594 | 200 µg/ml | $357.00 | |||
CD34 Antibody (B-6) Alexa Fluor® 647 | sc-74499 AF647 | 200 µg/ml | $357.00 | |||
CD34 Antibody (B-6) Alexa Fluor® 680 | sc-74499 AF680 | 200 µg/ml | $357.00 | |||
CD34 Antibody (B-6) Alexa Fluor® 790 | sc-74499 AF790 | 200 µg/ml | $357.00 |