BUB1 Antibody (14H5): sc-47743
- BUB1 Antibody (14H5) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- raised against full length recombinant human Bub1
- recommended for detection of BUB1 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for BUB1 Antibody (14H5) for WB applications. These reagents are now offered in bundles with BUB1 Antibody (14H5) (see ordering information below).
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BUB1 Antibody (14H5) is a mouse monoclonal IgG1 antibody that detects BUB1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BUB1 plays a critical role in the mitotic checkpoint, ensuring that chromosomes are properly aligned before cell division proceeds. BUB1 is primarily located at the kinetochore, a structure on the chromosome that is essential for the accurate segregation of chromosomes during mitosis. BUB1 localization at the kinetochore is vital because this positioning allows monitoring of interactions between kinetochores and microtubules, thereby preventing the onset of anaphase until all chromosomes are correctly positioned. Disruption of BUB1 function can lead to chromosomal instability and is implicated in various cancers, highlighting BUB1′s importance in maintaining genomic integrity. Anti-BUB1 antibody (14H5) is an invaluable tool for researchers studying cell cycle regulation and the mechanisms underlying mitotic errors.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BUB1 Antibody (14H5) | sc-47743 | 200 µg/ml | $322.00 | |||
BUB1 Antibody (14H5): m-IgG Fc BP-HRP Bundle | sc-536805 | 200 µg Ab; 10 µg BP | $361.00 | |||
BUB1 Antibody (14H5): m-IgGκ BP-HRP Bundle | sc-533970 | 200 µg Ab; 40 µg BP | $361.00 |