BTG2 Antibody (E-4): sc-518098
- BTG2 Antibody (E-4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 40-64 within an internal region of BTG2 of human origin
- BTG2 Antibody (E-4) is recommended for detection of BTG2 of human origin by WB, IP, IF and ELISA
- Anti-BTG2 Antibody (E-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for BTG2 Antibody (E-4) for WB applications. These reagents are now offered in bundles with BTG2 Antibody (E-4) (see ordering information below).
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BTG2 Antibody (E-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects BTG2 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BTG2 (E-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. BTG2 is a crucial member of the B cell translocation gene family, which plays a significant role in regulating cell proliferation and transcription. BTG2 functions as a p53-inducible protein that is vital for controlling the G1/S transition of the cell cycle, thereby acting as a tumor suppressor. BTG2 expression increases in response to DNA damage, cell differentiation, and quiescence, highlighting BTG2′s importance in cellular stress responses and growth regulation. High levels of BTG2 are predominantly found in kidney proximal tubules, lung alveolar bronchial epithelium, and the basal cell layer of prostate acini, indicating BTG2′s essential role in these tissues. BTG2 contains LXXLL motifs, which are critical for interaction with nuclear receptors, further emphasizing BTG2′s involvement in transcriptional regulation. BTG2′s ability to modulate cell cycle progression and respond to various cellular signals makes BTG2 a key player in maintaining cellular homeostasis and preventing uncontrolled cell growth.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BTG2 Antibody (E-4) | sc-518098 | 200 µg/ml | $316.00 | |||
BTG2 Antibody (E-4): m-IgG Fc BP-HRP Bundle | sc-528088 | 200 µg Ab; 10 µg BP | $354.00 | |||
BTG2 Antibody (E-4): m-IgG1 BP-HRP Bundle | sc-533461 | 200 µg Ab; 20 µg BP | $354.00 | |||
BTG2 Antibody (E-4) AC | sc-518098 AC | 500 µg/ml, 25% agarose | $416.00 | |||
BTG2 Antibody (E-4) HRP | sc-518098 HRP | 200 µg/ml | $316.00 | |||
BTG2 Antibody (E-4) FITC | sc-518098 FITC | 200 µg/ml | $330.00 | |||
BTG2 Antibody (E-4) PE | sc-518098 PE | 200 µg/ml | $343.00 | |||
BTG2 Antibody (E-4) Alexa Fluor® 488 | sc-518098 AF488 | 200 µg/ml | $357.00 | |||
BTG2 Antibody (E-4) Alexa Fluor® 546 | sc-518098 AF546 | 200 µg/ml | $357.00 | |||
BTG2 Antibody (E-4) Alexa Fluor® 594 | sc-518098 AF594 | 200 µg/ml | $357.00 | |||
BTG2 Antibody (E-4) Alexa Fluor® 647 | sc-518098 AF647 | 200 µg/ml | $357.00 | |||
BTG2 Antibody (E-4) Alexa Fluor® 680 | sc-518098 AF680 | 200 µg/ml | $357.00 | |||
BTG2 Antibody (E-4) Alexa Fluor® 790 | sc-518098 AF790 | 200 µg/ml | $357.00 |