BRD3 Antibody (B-12): sc-515666
- BRD3 Antibody (B-12) is a mouse monoclonal IgG2b κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 175-192 within an internal region of BRD3 of human origin
- Anti-BRD3 Antibody (B-12) is recommended for detection of BRD3 isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-BRD3 Antibody (B-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGκ BP-HRP is the preferred secondary detection reagent for BRD3 Antibody (B-12) for WB applications. This reagent is now offered in a bundle with BRD3 Antibody (B-12) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
BRD3 Antibody (B-12) is a mouse monoclonal IgG2b kappa light chain antibody that detects BRD3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-BRD3 antibody (B-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. BRD3, a member of the bromodomain-containing protein family, plays a crucial role in gene expression regulation by recognizing acetylated lysines on histones and non-histone proteins, which is essential for processes such as transcriptional activation and chromatin remodeling. Two bromodomains in BRD3 enable interactions with various transcriptional co-activators and chromatin remodeling complexes, thereby influencing cellular processes like differentiation and proliferation. BRD3 is encoded on chromosome 9q34 and participates in several cellular pathways, making BRD3 a significant target for research in cancer and other diseases. Bromodomain-containing proteins, including BRD2, BRD4, and BRDT, are widely expressed across different tissues, highlighting their importance in cellular function and potential as therapeutic targets.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BRD3 Antibody (B-12) | sc-515666 | 200 µg/ml | $316.00 | |||
BRD3 Antibody (B-12): m-IgGκ BP-HRP Bundle | sc-525153 | 200 µg Ab, 40 µg BP | $354.00 | |||
BRD3 Antibody (B-12) AC | sc-515666 AC | 500 µg/ml, 25% agarose | $416.00 | |||
BRD3 Antibody (B-12) HRP | sc-515666 HRP | 200 µg/ml | $316.00 | |||
BRD3 Antibody (B-12) FITC | sc-515666 FITC | 200 µg/ml | $330.00 | |||
BRD3 Antibody (B-12) PE | sc-515666 PE | 200 µg/ml | $343.00 | |||
BRD3 Antibody (B-12) Alexa Fluor® 488 | sc-515666 AF488 | 200 µg/ml | $357.00 | |||
BRD3 Antibody (B-12) Alexa Fluor® 546 | sc-515666 AF546 | 200 µg/ml | $357.00 | |||
BRD3 Antibody (B-12) Alexa Fluor® 594 | sc-515666 AF594 | 200 µg/ml | $357.00 | |||
BRD3 Antibody (B-12) Alexa Fluor® 647 | sc-515666 AF647 | 200 µg/ml | $357.00 | |||
BRD3 Antibody (B-12) Alexa Fluor® 680 | sc-515666 AF680 | 200 µg/ml | $357.00 | |||
BRD3 Antibody (B-12) Alexa Fluor® 790 | sc-515666 AF790 | 200 µg/ml | $357.00 | |||
BRD3 (B-12) Neutralizing Peptide | sc-515666 P | 100 µg/0.5 ml | $68.00 |