BAFF-R Antibody (11C1): sc-32774
- BAFF-R Antibody (11C1) is a mouse monoclonal IgG1 κ, cited in 8 publications, provided at 200 µg/ml
- raised against mouse B cell lymphoma L1.2 transfectants expressing BAFF-R of human origin
- recommended for detection of BAFF-R of human origin by IF, IHC(P) and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also provided azide-free for neutralization studies, sc-32774 L, 200 µg/0.1 ml
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for BAFF-R Antibody (11C1) for IHC(P) applications. These reagents are now offered in bundles with BAFF-R Antibody (11C1) (see ordering information below).
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SEE ALSO...
BAFF-R Antibody (11C1) is a mouse monoclonal IgG1 antibody that detects BAFF-R in human samples through applications such as immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). BAFF-R, also known as B cell activating factor receptor, plays a pivotal role in the immune system by regulating B cell survival and maturation. BAFF-R is primarily located on the surface of B cells, where BAFF-R interacts with TALL-1 to promote the transition of transitional B cells into mature B cells, which is essential for effective immune responses. BAFF-R expression is particularly high in the spleen and lymph nodes, indicating BAFF-R′s importance in lymphoid organ function and B cell development. Dysregulation of BAFF-R signaling has been implicated in various autoimmune diseases and lymphoproliferative disorders, making BAFF-R a critical target for therapeutic intervention. Anti-BAFF-R antibody (11C1) is an invaluable tool for researchers studying B cell biology and the underlying mechanisms of immune-related diseases.
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BAFF-R Antibody (11C1) References:
- BAFF receptor deficiency limits gammaherpesvirus infection. | Frederico, B., et al. 2014. J Virol. 88: 3965-75. PMID: 24501409
- Specific forms of BAFF favor BAFF receptor-mediated epithelial cell survival. | Lahiri, A., et al. 2014. J Autoimmun. 51: 30-7. PMID: 24602383
- BAFF receptor and TACI in B-1b cell maintenance and antibacterial responses. | Dickinson, GS., et al. 2015. Ann N Y Acad Sci. 1362: 57-67. PMID: 25962322
- B Cell Activating Factor (BAFF) and BAFF Receptor Expression in Autoimmune and Nonautoimmune Thyroid Diseases. | Campi, I., et al. 2015. Thyroid. 25: 1043-9. PMID: 26214745
- BAFF and BAFF-Receptor in B Cell Selection and Survival. | Smulski, CR. and Eibel, H. 2018. Front Immunol. 9: 2285. PMID: 30349534
- Treatment of primary Sjögren's syndrome with ianalumab (VAY736) targeting B cells by BAFF receptor blockade coupled with enhanced, antibody-dependent cellular cytotoxicity. | Dörner, T., et al. 2019. Ann Rheum Dis. 78: 641-647. PMID: 30826774
- BAFF receptor antibody for mantle cell lymphoma therapy. | Zhang, K., et al. 2021. Oncoimmunology. 10: 1893501. PMID: 33747637
- Modifications of the BAFF/BAFF-Receptor Axis in Patients With Pemphigus Treated With Rituximab Versus Standard Corticosteroid Regimen. | Hébert, V., et al. 2021. Front Immunol. 12: 666022. PMID: 34054835
- BAFF receptor polymorphisms and deficiency in humans. | Sevdali, E., et al. 2021. Curr Opin Immunol. 71: 103-110. PMID: 34311146
- BAFF antagonism via the BAFF receptor 3 binding site attenuates BAFF 60-mer-induced classical NF-κB signaling and metabolic reprogramming of B cells. | D Lempicki, M., et al. 2022. Cell Immunol. 381: 104603. PMID: 36182705
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BAFF-R Antibody (11C1) | sc-32774 | 200 µg/ml | $322.00 | |||
BAFF-R Antibody (11C1): m-IgG Fc BP-HRP Bundle | sc-538924 | 200 µg Ab; 10 µg BP | $361.00 | |||
BAFF-R Antibody (11C1): m-IgG1 BP-HRP Bundle | sc-541154 | 200 µg Ab; 20 µg BP | $361.00 | |||
BAFF-R Antibody (11C1) FITC | sc-32774 FITC | 200 µg/ml | $336.00 | |||
BAFF-R Antibody (11C1) L | sc-32774 L | 200 µg/0.1 ml | $322.00 | |||
BAFF-R Antibody (11C1) PE | sc-32774 PE | 200 µg/ml | $349.00 |