BAF170 Antibody (E-6): sc-17838
- BAF170 Antibody (E-6) is a mouse monoclonal IgG1 κ BAF170 antibody, cited in 33 publications, provided at 200 µg/ml
- raised against amino acids 1093-1208 of BAF170 of human origin
- BAF170 Antibody (E-6) is recommended for detection of BAF170 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-BAF170 Antibody (E-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for Gel Supershift and ChIP applications (sc-17838 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for BAF170 Antibody (E-6) for WB and IHC(P) applications. These reagents are now offered in bundles with BAF170 Antibody (E-6) (see ordering information below).
QUICK LINKS
BAF170 Antibody (E-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects BAF170 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). BAF170 (E-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. BAF170 plays a crucial role in the SWI/SNF chromatin remodeling complex, which is essential for the regulation of gene expression through ATP-dependent remodeling of nucleosome structure. This remodeling is vital for transcriptional activation, as BAF170 allows access to DNA for transcription factors and RNA polymerase. The functional core of the SWI/SNF complex includes BAF170, along with other key subunits such as Brm, Brg-1, Ini1, and BAF155, which work synergistically to enhance chromatin accessibility and facilitate the transcriptional machinery′s engagement with target genes. BAF170′s interaction with these subunits is critical for maintaining proper cellular function and responding to developmental cues, making BAF170 an important target for research in gene regulation and epigenetics.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
BAF170 Antibody (E-6) References:
- Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits. | Phelan, ML., et al. 1999. Mol Cell. 3: 247-53. PMID: 10078207
- A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor. | Muchardt, C. and Yaniv, M. 1993. EMBO J. 12: 4279-90. PMID: 8223438
- BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. | Khavari, PA., et al. 1993. Nature. 366: 170-4. PMID: 8232556
- ISWI, a member of the SWI2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor. | Tsukiyama, T., et al. 1995. Cell. 83: 1021-6. PMID: 8521502
- Nucleosome disruption by human SWI/SNF is maintained in the absence of continued ATP hydrolysis. | Imbalzano, AN., et al. 1996. J Biol Chem. 271: 20726-33. PMID: 8702824
- Cloning and mapping of SMARCA5 encoding hSNF2H, a novel human homologue of Drosophila ISWI. | Aihara, T., et al. 1998. Cytogenet Cell Genet. 81: 191-3. PMID: 9730600
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BAF170 Antibody (E-6) | sc-17838 | 200 µg/ml | $322.00 | |||
BAF170 Antibody (E-6): m-IgG Fc BP-HRP Bundle | sc-528331 | 200 µg Ab; 10 µg BP | $361.00 | |||
BAF170 Antibody (E-6): m-IgGκ BP-HRP Bundle | sc-520678 | 200 µg Ab, 40 µg BP | $361.00 | |||
BAF170 Antibody (E-6) X | sc-17838 X | 200 µg/0.1 ml | $322.00 | |||
BAF170 Antibody (E-6) AC | sc-17838 AC | 500 µg/ml, 25% agarose | $424.00 | |||
BAF170 Antibody (E-6) HRP | sc-17838 HRP | 200 µg/ml | $322.00 | |||
BAF170 Antibody (E-6) FITC | sc-17838 FITC | 200 µg/ml | $336.00 | |||
BAF170 Antibody (E-6) PE | sc-17838 PE | 200 µg/ml | $349.00 | |||
BAF170 Antibody (E-6) Alexa Fluor® 488 | sc-17838 AF488 | 200 µg/ml | $364.00 | |||
BAF170 Antibody (E-6) Alexa Fluor® 546 | sc-17838 AF546 | 200 µg/ml | $364.00 | |||
BAF170 Antibody (E-6) Alexa Fluor® 594 | sc-17838 AF594 | 200 µg/ml | $364.00 | |||
BAF170 Antibody (E-6) Alexa Fluor® 647 | sc-17838 AF647 | 200 µg/ml | $364.00 | |||
BAF170 Antibody (E-6) Alexa Fluor® 680 | sc-17838 AF680 | 200 µg/ml | $364.00 | |||
BAF170 Antibody (E-6) Alexa Fluor® 790 | sc-17838 AF790 | 200 µg/ml | $364.00 |