BAF170 Activators encompass a diverse group of chemical compounds that can either directly activate BAF170 or indirectly modulate its function by influencing specific signaling pathways. BAF170 is a key component of the SWI/SNF chromatin remodeling complex, playing a pivotal role in the regulation of chromatin structure and gene expression. These activators are essential tools for elucidating the regulatory mechanisms governing BAF170's role in epigenetic control. Direct activators, such as RSPO1, PMA, TPA, GSK3 Inhibitor IX, Lithium Chloride, BIO, SB-216763, 6-Bromoindirubin-3'-oxime, CHIR99021, Valproic Acid, and Rosiglitazone, exert their effects by either activating specific pathways or directly modifying BAF170. RSPO1, for instance, activates the canonical Wnt signaling pathway, indirectly influencing BAF170 through downstream signaling events that regulate chromatin remodeling. Similarly, PMA and TPA activate BAF170 by phosphorylation through PKC activation, enhancing chromatin remodeling processes. Meanwhile, GSK3 Inhibitors activate the Wnt/β-catenin pathway, indirectly impacting BAF170 by regulating downstream gene expression and chromatin remodeling.
These activators serve as powerful tools in understanding the intricate regulatory mechanisms of BAF170 in chromatin remodeling and gene expression control. By directly or indirectly modulating BAF170, they provide insights into the molecular pathways governing epigenetic regulation. In summary, BAF170 Activators are invaluable resources for studying the multifaceted roles of BAF170 in chromatin dynamics and gene expression. Whether through direct activation or pathway modulation, these chemicals enable researchers to unravel the complexities of epigenetic control and its implications in various biological processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a direct activator of BAF170, acting through protein kinase C (PKC) activation. PKC-mediated signaling pathways can modulate BAF170 function by phosphorylation, enhancing chromatin remodeling. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium Chloride is a direct activator of BAF170. It activates the Wnt/β-catenin pathway, indirectly modulating BAF170 by influencing downstream signaling events involved in chromatin remodeling. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $58.00 $188.00 $884.00 | 10 | |
GSK-3 Inhibitor IX is a direct activator of BAF170, acting through GSK3 inhibition and Wnt/β-catenin pathway activation. It indirectly modulates BAF170 by regulating chromatin remodeling processes. | ||||||
SB-216763 | 280744-09-4 | sc-200646 sc-200646A | 1 mg 5 mg | $71.00 $202.00 | 18 | |
SB-216763 is a direct activator of BAF170. It activates the Wnt/β-catenin pathway, indirectly influencing BAF170 by regulating downstream gene expression and chromatin remodeling. | ||||||
GSK-3 Inhibitor XVI | 252917-06-9 | sc-221691 sc-221691A | 5 mg 25 mg | $180.00 $610.00 | 4 | |
GSK-3 Inhibitor XVI is a direct activator of BAF170. It activates the Wnt/β-catenin signaling pathway, indirectly impacting BAF170 by regulating downstream gene expression and chromatin remodeling. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic Acid is a direct activator of BAF170. It influences histone deacetylase (HDAC) activity, indirectly modulating BAF170 by enhancing histone acetylation and chromatin remodeling. | ||||||
Rosiglitazone | 122320-73-4 | sc-202795 sc-202795A sc-202795C sc-202795D sc-202795B | 25 mg 100 mg 500 mg 1 g 5 g | $120.00 $326.00 $634.00 $947.00 $1259.00 | 38 | |
Rosiglitazone is a direct activator of BAF170. It activates the PPARγ pathway, indirectly influencing BAF170 function by regulating downstream gene expression and chromatin remodeling. | ||||||