ASK 1 Antibody (H-2): sc-390275

ASK 1 Antibody (H-2) is a mouse monoclonal IgM kappa antibody that detects ASK 1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ASK 1, also known as MAP3K5, plays a crucial role in cellular signaling pathways, particularly in the activation of mitogen-activated protein (MAP) kinase cascades, which are essential for mediating cellular responses to various extracellular stimuli, including stress and growth factors. ASK 1 is primarily located in the cytoplasm, where ASK 1 acts as a key regulator of apoptosis and inflammation by activating downstream kinases such as MEK-4 and MEK-3/MEK-6. This localization allows ASK 1 to respond rapidly to cellular stress signals, thereby influencing cell survival and death decisions. ASK 1′s ability to modulate these pathways underscores ASK 1′s importance in various physiological and pathological processes, including cancer and neurodegenerative diseases. Available in a non-conjugated form, anti-ASK 1 antibody (H-2) is an invaluable tool for researchers investigating the intricate signaling networks that govern cell fate and function.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ASK 1 Antibody (H-2) has 6 citations in a variety of scientific publications.

Primary antibodies like Anti-ASK 1 Antibody (H-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ASK 1 Antibody (H-2) Specifications

Alternate Product Name: MAP3K5

Product Clone Name: H-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 2-29

Epitope Target: ASK 1

Epitope Species: human

Product Reactivity/Detection: ASK 1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 6 citations in various scientific publications

Available Conjugates/Forms for ASK 1 Antibody (H-2): P: Blocking Peptide

The preferred ASK 1 antibody is ASK 1 Antibody (F-9): sc-5294.