ASK 1 Antibody (E-6): sc-390397
- ASK 1 Antibody (E-6) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-31 at the N-terminus of ASK 1 of human origin
- recommended for detection of ASK 1 of mouse, rat and human origin by WB, IP, IF and ELISA
- See ASK 1 (F-9): sc-5294 for ASK 1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for ASK 1 Antibody (E-6) for WB applications. This reagent is now offered in a bundle with ASK 1 Antibody (E-6) (see ordering information below).
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SEE ALSO...
ASK 1 Antibody (E-6) is a mouse monoclonal IgG2a antibody that detects ASK1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ASK1, or Apoptosis Signal-regulating Kinase 1, plays a crucial role in cellular stress responses, particularly in the activation of the c-Jun N-terminal kinase (JNK) and p38 MAPK pathways, which are essential for regulating apoptosis and inflammation. ASK1 mediates cellular responses to various stressors, including oxidative stress and pro-inflammatory cytokines, thereby influencing cell survival and death. Dysregulation of ASK1 has been implicated in several diseases, including cancer and neurodegenerative disorders, making ASK1 a significant target for therapeutic intervention. Anti-ASK1 antibody (E-6) provides a reliable tool for researchers aiming to study the functional dynamics of ASK1 in various biological contexts, facilitating a deeper understanding of ASK1′s role in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ASK 1 Antibody (E-6) | sc-390397 | 200 µg/ml | $322.00 | |||
ASK 1 Antibody (E-6): m-IgG Fc BP-HRP Bundle | sc-540798 | 200 µg Ab; 10 µg BP | $361.00 | |||
ASK 1 (E-6) Neutralizing Peptide | sc-390397 P | 100 µg/0.5 ml | $69.00 |