ARP-1 Antibody (A-5): sc-393500
- ARP-1 Antibody (A-5) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 157-184 near the N-terminus of ARP-1 of human origin
- recommended for detection of ARP-1 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, porcine and avian
- TransCruz reagent for ChIP application (sc-393500 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ARP-1 Antibody (A-5) for WB applications. These reagents are now offered in bundles with ARP-1 Antibody (A-5) (see ordering information below).
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SEE ALSO...
ARP-1 Antibody (A-5) is a mouse monoclonal IgG2a antibody that detects ARP-1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ARP-1, also known as COUP-TFII, plays a crucial role in various biological processes, particularly in gene expression regulation during development. ARP-1 is primarily located in the nucleus, where ARP-1 functions as a transcription factor, influencing the expression of genes involved in cellular differentiation and development. Nuclear localization of ARP-1 enables interaction with specific DNA response elements, thereby modulating target gene transcription. ARP-1 has been shown to interact with other transcription factors, such as retinoic acid receptors and peroxisome proliferator-activated receptors, which underscores ARP-1′s importance in coordinating complex gene regulatory networks. ARP-1′s ability to act as both a negative regulator and transcription initiator highlights ARP-1′s versatile role in cellular processes, making ARP-1 a significant focus of research in developmental biology and disease mechanisms.
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ARP-1 Antibody (A-5) References:
- Involvement of Ad4BP/SF-1, DAX-1, and COUP-TFII transcription factor on steroid production and luteinization in ovarian theca cells. | Murayama, C., et al. 2008. Mol Cell Biochem. 314: 51-8. PMID: 18409030
- COUP-TFII inhibits NFkappaB activation in endocrine-resistant breast cancer cells. | Litchfield, LM., et al. 2014. Mol Cell Endocrinol. 382: 358-367. PMID: 24141032
- COUP-TFII regulates metastasis of colorectal adenocarcinoma cells by modulating Snail1. | Bao, Y., et al. 2014. Br J Cancer. 111: 933-43. PMID: 25032732
- COUP-TFII Stimulates Dentin Sialophosphoprotein Expression and Mineralization in Odontoblasts. | Hur, SW., et al. 2015. J Dent Res. 94: 1135-42. PMID: 25940145
- Overexpression of COUP‑TFII suppresses proliferation and metastasis of human gastric cancer cells. | Ding, W., et al. 2018. Mol Med Rep. 17: 2393-2401. PMID: 29207189
- Downregulation of COUP-TFII inhibits glioblastoma growth via targeting MPC1. | Xiao, B., et al. 2018. Oncol Lett. 15: 9697-9702. PMID: 29928345
- Orphan nuclear receptor COUP-TFII is an oncogenic gene in renal cell carcinoma. | Fang, X., et al. 2020. Clin Transl Oncol. 22: 772-781. PMID: 31368079
- Isoforms of the orphan nuclear receptor COUP‑TFII differentially modulate pancreatic cancer progression. | Polvani, S., et al. 2022. Int J Oncol. 60: PMID: 35348189
- COUP-TFII plays a role in cAMP-induced Schwann cell differentiation and in vitro myelination by up-regulating Krox20. | Han, SH., et al. 2023. J Neurochem. 165: 660-681. PMID: 36648143
- Localization of transcripts of the related nuclear orphan receptors COUP-TF I and ARP-1 in the adult mouse brain. | Lopes da Silva, S., et al. 1995. Brain Res Mol Brain Res. 30: 131-6. PMID: 7609634
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARP-1 Antibody (A-5) | sc-393500 | 200 µg/ml | $322.00 | |||
ARP-1 Antibody (A-5): m-IgG Fc BP-HRP Bundle | sc-538232 | 200 µg Ab; 10 µg BP | $361.00 | |||
ARP-1 Antibody (A-5): m-IgGκ BP-HRP Bundle | sc-535804 | 200 µg Ab; 40 µg BP | $361.00 | |||
ARP-1 Antibody (A-5): m-IgG2a BP-HRP Bundle | sc-548241 | 200 µg Ab; 10 µg BP | $361.00 | |||
ARP-1 (A-5) Neutralizing Peptide | sc-393500 P | 100 µg/0.5 ml | $69.00 | |||
ARP-1 Antibody (A-5) X | sc-393500 X | 200 µg/0.1 ml | $322.00 |