AQP4 Antibody (F-7) is a mouse monoclonal IgG1 antibody that detects Aquaporin 4 (AQP4) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). AQP4 plays a crucial role in maintaining water homeostasis in various tissues, particularly in the brain and skeletal muscle, where AQP4 is predominantly localized to the sarcolemma of fast-twitch muscle fibers. This localization allows for efficient water transport across the cell membrane, which is essential for muscle contraction and overall muscle function. AQP4′s ability to facilitate rapid water movement is particularly important in osmotic regulation and cellular hydration, impacting processes such as muscle performance and recovery. AQP4 is also involved in the regulation of cerebrospinal fluid dynamics, highlighting AQP4′s significance in both muscular and neurological health. With broad species reactivity and versatility in various applications, anti-AQP4 antibody (F-7) serves as an invaluable tool for researchers studying the physiological and pathological roles of this important water channel protein.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Aquaporin 4/AQP4 Antibody (F-7) | sc-390636 | 200 µg/ml | $316.00 | |||
Aquaporin 4/AQP4 Antibody (F-7): m-IgG Fc BP-HRP Bundle | sc-540825 | 200 µg Ab; 10 µg BP | $354.00 | |||
Aquaporin 4/AQP4 Antibody (F-7): m-IgG1 BP-HRP Bundle | sc-542396 | 200 µg Ab; 20 µg BP | $354.00 |