API5 Antibody (D-1): sc-393341
- API5 Antibody (D-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 72-103 near the N-terminus of API5 of human origin
- recommended for detection of API5 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for API5 Antibody (D-1) for WB and IHC(P) applications. These reagents are now offered in bundles with API5 Antibody (D-1) (see ordering information below).
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SEE ALSO...
API5 Antibody (D-1) is a mouse monoclonal IgG1 antibody that detects API5 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). API5, also known as apoptosis inhibitor 5, AAC11, FIF, MIG8, XAGL, or API5L1, is a crucial antiapoptotic nuclear protein that plays a significant role in cellular survival and proliferation. API5 is characterized by nuclear localization sequence, LxxLL motif, leucine zipper domain, and transactivation domain, which are essential for function as a transcription regulator. Notably, API5 is involved in the regulation of matrix metalloproteinase-2 (MMP-2) synthesis, a key player in extracellular matrix remodeling and tumor progression. API5′s ability to form a nuclear complex with fibroblast growth factor 2 (FGF-2) highlights importance in mediating FGF-2-dependent signaling pathways, which are critical for various cellular processes, including angiogenesis and tissue repair. Furthermore, API5′s expression is often linked to the degree of malignancy in various cancer cell lines, making API5 a potential biomarker for tumor progression and a target for therapeutic intervention. anti-API5 antibody (D-1) is an invaluable tool for researchers studying apoptosis, cancer biology, and related fields.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
API5 Antibody (D-1) | sc-393341 | 200 µg/ml | $322.00 | |||
API5 Antibody (D-1): m-IgG Fc BP-HRP Bundle | sc-538191 | 200 µg Ab; 10 µg BP | $361.00 | |||
API5 Antibody (D-1): m-IgGκ BP-HRP Bundle | sc-535757 | 200 µg Ab; 40 µg BP | $361.00 | |||
API5 Antibody (D-1): m-IgG1 BP-HRP Bundle | sc-545567 | 200 µg Ab; 20 µg BP | $361.00 | |||
API5 (D-1) Neutralizing Peptide | sc-393341 P | 100 µg/0.5 ml | $69.00 |