APCDD1L Antibody (F-5): sc-398858
- APCDD1L Antibody (F-5) is a mouse monoclonal IgG1 κ APCDD1L antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 448-472 near the C-terminus of APCDD1L of human origin
- APCDD1L Antibody (F-5) is recommended for detection of APCDD1L of human origin by WB, IP, IF and ELISA
- Anti-APCDD1L Antibody (F-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for APCDD1L Antibody (F-5) for WB applications. These reagents are now offered in bundles with APCDD1L Antibody (F-5) (see ordering information below).
QUICK LINKS
APCDD1L Antibody (F-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects APCDD1L protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). APCDD1L (F-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. APCDD1L protein, also known as adenomatosis polyposis coli down-regulated 1, is a 514 amino acid single-pass type I membrane protein that plays a crucial role in the regulation of the β-catenin signaling pathway, which is vital for cellular processes such as proliferation and differentiation. APCDD1L protein is predominantly expressed in the ovary, heart, pancreas, and prostate, with lower expression levels found in the spleen, lung, kidney, liver, and colon. APCDD1L′s significance lies in its potential involvement in colorectal tumorigenesis, as APCDD1L acts as a developmental target of the β-catenin pathway, highlighting APCDD1L′s importance in cancer research. The gene encoding human APCDD1L is located on chromosome 18, a region associated with various genetic disorders, including Trisomy 18 and hereditary hemorrhagic telangiectasia, underscoring APCDD1L′s clinical relevance in understanding disease mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
APCDD1L Antibody (F-5) References:
- Does PRNP gene control the clinical and pathological phenotype of human spongiform transmissible encephalopathies? | Masullo, C. and Macchi, G. 2001. Clin Neuropathol. 20: 19-25. PMID: 11220690
- Gerstmann-Sträussler-Scheinker syndrome,fatal familial insomnia, and kuru: a review of these less common human transmissible spongiform encephalopathies. | Collins, S., et al. 2001. J Clin Neurosci. 8: 387-97. PMID: 11535002
- Isolation of a novel human gene, APCDD1, as a direct target of the beta-Catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis. | Takahashi, M., et al. 2002. Cancer Res. 62: 5651-6. PMID: 12384519
- Early pattern of epilepsy in the ring chromosome 20 syndrome. | Ville, D., et al. 2006. Epilepsia. 47: 543-9. PMID: 16529619
- Trisomy 20 mosaicism and nonmosaic trisomy 20: a report of 2 cases. | Joó, JG., et al. 2006. J Reprod Med. 51: 209-12. PMID: 16674019
- Eppin: an epididymal protease inhibitor and a target for male contraception. | O'Rand, MG., et al. 2007. Soc Reprod Fertil Suppl. 63: 445-53. PMID: 17566290
- A locus on chromosome 20 encompassing genes that are highly expressed in the epididymis. | Lundwall, A. 2007. Asian J Androl. 9: 540-4. PMID: 17589793
- Ring chromosome 20 syndrome without deletions of the subtelomeric and CHRNA4--KCNQ2 genes loci. | Elghezal, H., et al. 2007. Eur J Med Genet. 50: 441-5. PMID: 17851150
- Cellular pathways leading to neuronal dysfunction and degeneration. | Kazantsev, AG. 2007. Drug News Perspect. 20: 501-9. PMID: 18080037
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
APCDD1L Antibody (F-5) | sc-398858 | 200 µg/ml | $322.00 | |||
APCDD1L Antibody (F-5): m-IgG Fc BP-HRP Bundle | sc-530944 | 200 µg Ab; 10 µg BP | $361.00 | |||
APCDD1L Antibody (F-5): m-IgGκ BP-HRP Bundle | sc-524507 | 200 µg Ab, 40 µg BP | $361.00 | |||
APCDD1L Antibody (F-5): m-IgG1 BP-HRP Bundle | sc-544330 | 200 µg Ab; 20 µg BP | $361.00 | |||
APCDD1L Antibody (F-5) AC | sc-398858 AC | 500 µg/ml, 25% agarose | $424.00 | |||
APCDD1L Antibody (F-5) HRP | sc-398858 HRP | 200 µg/ml | $322.00 | |||
APCDD1L Antibody (F-5) FITC | sc-398858 FITC | 200 µg/ml | $336.00 | |||
APCDD1L Antibody (F-5) PE | sc-398858 PE | 200 µg/ml | $349.00 | |||
APCDD1L Antibody (F-5) Alexa Fluor® 488 | sc-398858 AF488 | 200 µg/ml | $364.00 | |||
APCDD1L Antibody (F-5) Alexa Fluor® 546 | sc-398858 AF546 | 200 µg/ml | $364.00 | |||
APCDD1L Antibody (F-5) Alexa Fluor® 594 | sc-398858 AF594 | 200 µg/ml | $364.00 | |||
APCDD1L Antibody (F-5) Alexa Fluor® 647 | sc-398858 AF647 | 200 µg/ml | $364.00 | |||
APCDD1L Antibody (F-5) Alexa Fluor® 680 | sc-398858 AF680 | 200 µg/ml | $364.00 | |||
APCDD1L Antibody (F-5) Alexa Fluor® 790 | sc-398858 AF790 | 200 µg/ml | $364.00 | |||
APCDD1L (F-5) Neutralizing Peptide | sc-398858 P | 100 µg/0.5 ml | $69.00 |