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Annexin II Antibody (H-3) is a mouse monoclonal IgG1 kappa light chain antibody raised against a peptide mapping near the N-terminus of human Annexin II, also known as Annexin A2, p36, Calpactin I heavy chain, Chromobindin-8, and Lipocortin II. Anti-Annexin II antibody (H-3) detects Annexin II from mouse, rat, human, and additional species including equine, canine, bovine, and porcine origins by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Annexin II is a calcium-dependent phospholipid-binding protein involved in various cellular processes such as membrane trafficking, endocytosis, exocytosis, and cellular adhesion. Annexin II functions as a key mediator in fibrinolysis by acting as a co-receptor for tissue plasminogen activator (tPA) and plasminogen, facilitating the conversion of plasminogen to plasmin, which is essential for blood clot breakdown. The protein forms a heterotetramer with S100A10 (p11), known as calpactin I, which is crucial for its role in signal transduction and cytoskeletal organization. Understanding the function of Annexin II is important because this protein is implicated in physiological processes like inflammation, angiogenesis, and tumor progression. Annexin II monoclonal antibody (H-3) is available in both unconjugated and multiple conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates, providing versatility for a wide range of experimental applications. Anti-Annexin II antibody (H-3) enables researchers to investigate Annexin II′s role in health and disease, making this tool valuable in biomedical research.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Annexin-2/ANXA2 Antibody (H-3) | sc-271175 | 200 µg/ml | $322.00 | |||
Annexin-2/ANXA2 Antibody (H-3): m-IgG Fc BP-HRP Bundle | sc-537580 | 200 µg Ab; 10 µg BP | $361.00 | |||
Annexin-2/ANXA2 Antibody (H-3): m-IgGκ BP-HRP Bundle | sc-534885 | 200 µg Ab; 40 µg BP | $361.00 | |||
Annexin-2/ANXA2 Antibody (H-3): m-IgG1 BP-HRP Bundle | sc-545242 | 200 µg Ab; 20 µg BP | $361.00 | |||
Annexin-2/ANXA2 (H-3) Neutralizing Peptide | sc-271175 P | 100 µg/0.5 ml | $69.00 |